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Cognitive Rehabilitation for Mild Cognitive Impairment

N/A

Recruiting

Led By Elizabeth W. Twamley, PhD

Research Sponsored by VA Office of Research and Development

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Independently living

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 1, 2, 3, 4, 5, 6, 7, 8, 21 weeks

Awards & highlights

Study Summary

This trial is testing a new cognitive training intervention that may help Veterans with Mild Cognitive Impairment (MCI).

Who is the study for?

This trial is for Veterans over 55 with Mild Cognitive Impairment (MCI), who can consent to the study, live independently, and do not have dementia. They must be enrolled at certain VA sites, express concern about cognitive decline, and show impairment in functions like memory or attention. Those with recent substance abuse, significant brain injury, or major psychiatric disorders cannot join.Check my eligibility

What is being tested?

The trial tests two non-drug treatments for MCI in older Veterans: Goal-focused Supportive Contact and Motivationally Enhanced Compensatory Cognitive Training. It aims to improve daily functioning by teaching strategies to compensate for cognitive deficits.See study design

What are the potential side effects?

Since this trial involves cognitive training rather than medication, traditional physical side effects are not expected. Participants may experience fatigue or frustration during the exercises but no medical side effects.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I live on my own.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 1, 2, 3, 4, 5, 6, 7, 8, 21 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 1, 2, 3, 4, 5, 6, 7, 8, 21 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1, 2, 3, 4, 5, 6, 7, 8, 21 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Functional capacity performance composite z score

Change in Objective cognitive performance composite z score

Secondary outcome measures

Change in CHAMPS Physical Activity Questionnaire for Older Adults

Change in Cognitive Activity Inventory

Change in Everyday Cognition Scale

+4 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: ME-CCTExperimental Treatment1 Intervention

8-week Motivationally Enhanced Compensatory Cognitive Training group

Group II: SCActive Control1 Intervention

8-week Goal-focused Supportive Contact group

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor

1,609 Previous Clinical Trials

3,306,387 Total Patients Enrolled

Portland VA Medical CenterFED

41 Previous Clinical Trials

7,149 Total Patients Enrolled

Elizabeth W. Twamley, PhDPrincipal InvestigatorVA San Diego Healthcare System, San Diego, CA

3 Previous Clinical Trials

242 Total Patients Enrolled

Media Library

Motivationally Enhanced Compensatory Cognitive Training Clinical Trial Eligibility Overview. Trial Name: NCT03225482 — N/A

Mild Cognitive Impairment Research Study Groups: ME-CCT, SC

Motivationally Enhanced Compensatory Cognitive Training 2023 Treatment Timeline for Medical Study. Trial Name: NCT03225482 — N/A

Mild Cognitive Impairment Clinical Trial 2023: Motivationally Enhanced Compensatory Cognitive Training Highlights & Side Effects. Trial Name: NCT03225482 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacancies for participants in this trial?

"According to clinicaltrials.gov, this trial is presently recruiting participants; the listing was first created on July 11th 2018 and most recently updated on January 19th 2022."

Answered by AI

What is the desired outcome of this research experiment?

"This clinical trial, evaluated at three points: baseline, 8 weeks, and 21 weeks will seek to measure a change in objective cognitive performance composite z-score. Additionally, secondary outcomes include changes in subjective functioning composite score average total score across applied cognition executive function and applied cognition general concerns scales; sleep efficiency (measured by Fitbit); and Everyday Cognition Scale Total Score."

Answered by AI

How many individuals have been accepted to participate in this research endeavor?

"Yes, the data available on clinicaltrials.gov reveals that recruitment is underway for this medical trial. It was initially advertised on July 11th 2018 and last updated on January 19th 2022; a total of 216 patients are needed to be recruited from two different centres."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Cognitive Rehabilitation Therapy for Mild Cognitive Impairment

2018. "Cognitive Rehabilitation Therapy for Mild Cognitive Impairment". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03225482.

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