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Noninvasive Brain Stimulation

Active rTMS (Bilateral LPC) for Mild Cognitive Impairment

N/A

Waitlist Available

Led By Joy L Taylor, Ph.D.

Research Sponsored by Palo Alto Veterans Institute for Research

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 1 week after completing the 20-session intervention

Awards & highlights

Study Summary

This trial is testing whether electrical stimulation to the brain can help people with mild cognitive impairment.

Eligible Conditions

Mild Cognitive Impairment
Memory Loss
Cognitive Impairment
Cognitive Decline

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 1 week after completing the 20-session intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 1 week after completing the 20-session intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1 week after completing the 20-session intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change from Baseline in memory score, as measured by the California Verbal Learning Test-II (CVLT-II)

Secondary outcome measures

Change from Baseline in CVLT-II Semantic clustering

Change from Baseline in CVLT-II Short-delay free recall

Change from Baseline in attention, as measured by the Attentional Network Test (ANT)

+11 more

Trial Design

3Treatment groups

Experimental Treatment

Placebo Group

Group I: Active rTMS (Bilateral LPC)Experimental Treatment1 Intervention

One-third of participants will receive active rTMS to the right and left lateral parietal cortex (LPC).

Group II: Active rTMS (Bilateral DLPFC)Experimental Treatment1 Intervention

One-third of participants will receive active rTMS to the right and left dorsolateral prefrontal cortex (DLPFC).

Group III: Placebo rTMS (Inactive)Placebo Group1 Intervention

One-third of participants will receive placebo/inactive rTMS, either to the DLPFC or the LPC. Those receiving placebo rTMS will serve as the control group.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Active rTMS (Bilateral LPC)

2018

N/A

~40

Active rTMS (Bilateral DLPFC)

2018

N/A

~40

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

National Institute on Aging (NIA)NIH

1,671 Previous Clinical Trials

28,017,023 Total Patients Enrolled

Palo Alto Veterans Institute for ResearchLead Sponsor

52 Previous Clinical Trials

7,865 Total Patients Enrolled

Joy L Taylor, Ph.D.Principal InvestigatorStanford/VA Aging Clinical Center

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

If I meet the requirements, may I join this research project?

"This trial is searching for 99 individuals between the ages of 55 and 90 who are experiencing cognitive decline. In addition to this, participants must also: Be generally healthy with no pre-existing conditions that would interfere with the study;, Have a Modified Hachinski Ischemic score of 4 or less;, Be unable to get pregnant or be of childbearing potential (i.e. women must be 2 years post-menopausal or surgically sterile);, Have stable medications (including any dementia-related meds) for at least 4 weeks prior to Baseline;, Be a Veteran or Non-Veteran that meets the following"

Answered by AI

Will this research include elderly test subjects?

"This trial is only for patients that are between the ages of 55 and 90, as specified in the eligibility requirements."

Answered by AI

Can new patients still join this ongoing clinical trial?

"Unfortunately, this particular clinical trial is not enrolling new patients at this time. This is according to the latest update on the study, which was posted on July 5th, 2022. Although this specific study is not taking any more participants, there are 632 other trials that are actively looking for patients."

Answered by AI