RLIC for Cerebral Palsy

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Cerebral PalsyRLIC - Behavioral
Eligibility
6 - 16
All Sexes
What conditions do you have?
Select

Study Summary

This trial will investigate if a non-invasive treatment can improve power, balance, and walking in children with cerebral palsy.

Treatment Effectiveness

Study Objectives

3 Primary · 3 Secondary · Reporting Duration: Pre-intervention to 1 month post-intervention follow-up

Month 1
Change in Balance Score
Change in Peak knee extension power
Change in Walking Speed
Gait Analysis
Lower limb activity
Quadriceps Electromyography

Trial Safety

Trial Design

2 Treatment Groups

Remote Limb Ischemic Conditioning (RLIC)
1 of 2
Sham Conditioning
1 of 2

Experimental Treatment

Non-Treatment Group

24 Total Participants · 2 Treatment Groups

Primary Treatment: RLIC · Has Placebo Group · N/A

Remote Limb Ischemic Conditioning (RLIC)Experimental Group · 4 Interventions: Treadmill Training, Balance training, RLIC, Muscle Power training · Intervention Types: Behavioral, Behavioral, Behavioral, Behavioral
Sham ConditioningShamComparator Group · 4 Interventions: Treadmill Training, Sham Conditioning, Balance training, Muscle Power training · Intervention Types: Behavioral, Behavioral, Behavioral, Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Treadmill Training
2009
Completed Phase 1
~120
Balance training
2014
Completed Phase 1
~650
RLIC
2015
Completed Phase 1
~120

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: pre-intervention to 1 month post-intervention follow-up

Who is running the clinical trial?

East Carolina UniversityLead Sponsor
95 Previous Clinical Trials
35,296 Total Patients Enrolled
1 Trials studying Cerebral Palsy
30 Patients Enrolled for Cerebral Palsy
Swati M Surkar, PT, PhDPrincipal InvestigatorAssistant Professor, East Carolina University

Eligibility Criteria

Age 6 - 16 · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a gross motor function classification system (GMFCS) level I-III.
References