HMB + Vitamin D3 for Cerebral Palsy
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify if you need to stop taking your current medications. However, if you have prescription drug or nutrition supplement contraindications (reasons not to take them together), you may not be eligible to participate.
What data supports the effectiveness of the treatment HMB + Vitamin D3 for cerebral palsy?
How does the HMB + Vitamin D3 treatment for cerebral palsy differ from other treatments?
The HMB + Vitamin D3 treatment is unique because it combines HMB, which may help with muscle health, with Vitamin D3, which is crucial for bone health and is often deficient in children with cerebral palsy. This combination targets both muscle and bone issues, which are common in cerebral palsy, unlike other treatments that may focus on just one aspect.34567
What is the purpose of this trial?
This trial tests a daily supplement of HMB and Vitamin D3 in adolescents with cerebral palsy over a few months. It aims to see if the supplement is safe and acceptable, and whether it improves muscle strength and mobility. HMB and vitamin D3 supplementation has been studied for enhancing muscle strength and physical functionality in older adults, even in individuals not engaged in an exercise training program.
Eligibility Criteria
Adolescents aged 13-17 with cerebral palsy, specifically those who are ambulatory (GMFCS Level I-III) and can follow directions including taking pills daily. They should live near the University of Minnesota, read English, and not be pregnant or planning to become pregnant. Excluded if they've had recent surgeries or certain treatments that affect muscle strength.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive daily combined HMB + Vitamin D3 supplementation
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- HMB
- Vitamin D3
Find a Clinic Near You
Who Is Running the Clinical Trial?
Gillette Children's Specialty Healthcare
Lead Sponsor
University of Minnesota
Collaborator
Metabolic Technologies, LLC
Collaborator