Study Summary
This trial looks at children with two-sided cerebral palsy to see how their legs are affected when they take steps.
Eligible Conditions
- Bilateral Cerebral Palsy
- Diplegic Cerebral Palsy
- Cerebral Palsy
Treatment Effectiveness
Effectiveness Progress
Study Objectives
4 Primary · 3 Secondary · Reporting Duration: At baseline and each loading level; During entirety of the stepping trial, from initial lift-off to final contact onto the single platform.
At baseline and each loading level; During entirety of the stepping trial, from initial lift-off to final contact onto the single platform.
Joint biomechanics (ankle)
Joint biomechanics (hip)
Joint biomechanics (knee)
Joint biomechanics (support moment)
Muscle activations (ankle)
Muscle activations (hip)
Muscle activations (knee)
Trial Safety
Safety Progress
Trial Design
1 Treatment Group
load modulation
1 of 1
Experimental Treatment
30 Total Participants · 1 Treatment Group
Primary Treatment: load modulation · No Placebo Group · N/A
load modulation
Other
Experimental Group · 1 Intervention: load modulation · Intervention Types: OtherTrial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: at baseline and each loading level; during entirety of the stepping trial, from initial lift-off to final contact onto the single platform.
Who is running the clinical trial?
Northwestern UniversityLead Sponsor
1,455 Previous Clinical Trials
789,664 Total Patients Enrolled
Eligibility Criteria
Age 5 - 19 · All Participants · 3 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:You are able to step up independently with or without assistive devices.
You have cerebral palsy and have a diagnosis of bilateral cerebral palsy where the lower limbs are more affected than the upper limbs.
References
- Novak, A.C., and B. Brouwer. 2011. “Sagittal and Frontal Lower Limb Joint Moments During Stair Ascent and Descent in Young and Older Adults”. Gait & Posture. Elsevier BV. doi:10.1016/j.gaitpost.2010.09.024.
- Lepage, Céline, Luc Noreau, and Paul-Marie Bernard. 1998. “Association Between Characteristics of Locomotion and Accomplishment of Life Habits in Children with Cerebral Palsy”. Physical Therapy. Oxford University Press (OUP). doi:10.1093/ptj/78.5.458.
- ROSE, JESSICA. 2009. “Selective Motor Control in Spastic Cerebral Palsy”. Developmental Medicine & Child Neurology. Wiley. doi:10.1111/j.1469-8749.2009.03401.x.
- FOWLER, EILEEN G, LORETTA A STAUDT, and MARCIA B GREENBERG. 2010. “Lower-extremity Selective Voluntary Motor Control in Patients with Spastic Cerebral Palsy: Increased Distal Motor Impairment”. Developmental Medicine & Child Neurology. Wiley. doi:10.1111/j.1469-8749.2009.03586.x.
- Rose J. Selective motor control in spastic cerebral palsy. Dev Med Child Neurol. 2009 Aug;51(8):578-9. doi: 10.1111/j.1469-8749.2009.03401.x. No abstract available.
- Lepage C, Noreau L, Bernard PM. Association between characteristics of locomotion and accomplishment of life habits in children with cerebral palsy. Phys Ther. 1998 May;78(5):458-69. doi: 10.1093/ptj/78.5.458.
- Theresa Moulton 2021. "Stepping to Understand Lower Limb Impairments in Bilateral Cerebral Palsy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04957277.
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Conditions
Cancer Related
Treatments