This trial is evaluating whether Aerobic Training will improve 1 primary outcome and 6 secondary outcomes in patients with Hypermetria. Measurement will happen over the course of 6 months.
This trial requires 48 total participants across 2 different treatment groups
This trial involves 2 different treatments. Aerobic Training is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"Cerebellar diseases are a common group of brain disorders that result in motor and gait disorders and often have symptoms similar to those of Parkinson's disease and Alzheimer's disease. The cerebellum's main functions include balance and coordination, as well as fine motor skills and processing sensory information. Cerebellar diseases manifest themselves as gait disorders. Patients with either cerebellar disease or a subtype of the cerebellar disorders often present with ataxia, incoordination, slowed movement, dysarthria (excessive noise in speech), and dysdiadochokinesia (a form of dysmetria, irregularity of movement)." - Anonymous Online Contributor
"Signs and symptoms of cerebellar diseases include neck rigidity, abnormal balance when standing, and gait abnormality when walking. Some forms of cerebellar diseases cause unsteady gait or staggering. Hearing loss is another sign. In some cases, the signs and symptoms of cerebellar diseases are quite subtle. If all of those signs are present in a patient’s history and on physical exam, medical professionals should consider an underlying cerebellar disease." - Anonymous Online Contributor
"Based on the present analysis the number of new cases in the USA per year is about 30/100,000. Approximately, 2 cases per 100,000 are diagnosed in people over 50 years of age. Of the 40,000 reported cases, 15,000 are new. However, 2 cases in 10,000 people die from cerebellar diseases. More information is needed to explain some of puzzling phenomena reported." - Anonymous Online Contributor
"The most common causes of cerebellar diseases are congenital trauma and neurodegenerative disorders. Both congenital and neurodegenerative disorders cause cerebellar diseases, while neurodegenerative disorders often cause many kinds of cerebrovascular-related diseases as well and are therefore the main causes of cerebellar diseases. Patients with cerebellar diseases and their parents must be followed up and made aware on the proper way to prevent or treat diseases." - Anonymous Online Contributor
"More than 40% of the patients had no medication prescription before beginning medical treatment for cerebellar diseases. In the current study, only a considerable minority used at-home physical and/or occupational therapy. The prescribed treatment depended significantly on the initial severity and a few other factors. The most common therapy was at-home physical, occupational and/or speech therapy. The prescribed treatment differed significantly between the disorders." - Anonymous Online Contributor
"In a recent study, findings shows the necessity of a strict definition of "cure" for rehabilitation studies and their application in the clinical management of both patients and families." - Anonymous Online Contributor
"The most common cause of cerebellar diseases is idiopathic and its frequency is similar in all age groups. A definite correlation has been shown between the onset of cerebellar disease and the occurrence of hypertension and obesity which are frequently encountered in patients with cerebellar diseases." - Anonymous Online Contributor
"Data from a recent study, which utilized double-blind random assignment, revealed that aerobic training was more effective than a placebo. This information deserves attention when designing and conducting large prospective trials on chronic degenerative diseases, if it is applicable that chronic degenerative diseases result from physical inactivity. However, it is still unknown whether the prevention or improvement programs of chronic degenerative diseases by exercise could be conducted, and exercise should be chosen according to the disease condition." - Anonymous Online Contributor
"Aerobic training is safe and can lead to a clinically relevant response in selected patients with neurological conditions such as stroke. The underlying mechanisms should be further studied in order to develop exercise programs for patients with neurological conditions." - Anonymous Online Contributor
"The present studies show that one of the benefits of the aerobic exercise is the recovery of brain function and that, consequently, more and more patients can have a complete recovery." - Anonymous Online Contributor
"Current therapies are effective in treating cerebellar diseases; however, new technologies are needed in the development of treatments because cerebellar diseases are challenging to treat due to the brain's resilience." - Anonymous Online Contributor
"The current literature includes a large amount of high quality randomized controlled trials comparing aerobic exercise to no exercise in various patient groups. The scope of the methodological limitations included in both primary research and reviews is broadened by the use of more specific and high-quality techniques, such as meta-analyses rather than systematic reviews. The effect of confounding variables including treatment intensity, type of exercise, and lifestyle behaviors cannot be ruled out. The current scope of methodological limitations in the scientific literature on aerobic exercise for therapeutic use is widened by careful consideration of the methodological quality of primary and recent reviews. Further prospective trials in well-defined patient groups are needed to establish the effect of exercise in cardiovascular, cardiovascular risk, neurological and psychiatric, and musculoskeletal conditions." - Anonymous Online Contributor