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Saliva Insulin as Biomarker of Risk Factors for Metabolic Dysregulation and Cavities

N/A

Recruiting

Led By Thomas Tanbonliong, DDS

Research Sponsored by Jodi Stookey

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 hour

Awards & highlights

Study Summary

This trial explores if saliva insulin monitoring can be used to track the success of interventions to prevent obesity, diabetes & caries in kids, without relying on self-reported measures.

Eligible Conditions

Cavities
Metabolomic Profile

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 hour

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 hour

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 hour for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Lower saliva insulin after drinking water compared to juice; compared to no drink

Secondary outcome measures

Different untargeted metabolomic profile after drinking water compared to juice; and after drinking water compared to no drink

Higher saliva buffering capacity after drinking water than after apple juice or no drink

Higher saliva pH (potential of hydrogen) after drinking water than after apple juice or no drink

+1 more

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Group I: Drinking waterExperimental Treatment1 Intervention

Intervention drink; Participants will receive 500 ml drinking water from the San Francisco tap (i.e. fluoridated tap water). 500 ml is the standard bottle size.

Group II: No drinkActive Control1 Intervention

Control; Participants will receive no drink

Group III: Apple juiceActive Control1 Intervention

Intervention drink; Participants will receive 200 ml box of apple juice. 200 ml is the standard serving usually available to this study population in the school setting

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Jodi StookeyLead Sponsor

Thomas Tanbonliong, DDSPrincipal InvestigatorUniversity of California, San Francisco

Mimansa Cholera, DDSPrincipal InvestigatorUniversity of California, San Francisco

Media Library

Drinking water (Other) Clinical Trial Eligibility Overview. Trial Name: NCT05211843 — N/A

Cavities Research Study Groups: No drink, Drinking water, Apple juice

Cavities Clinical Trial 2023: Drinking water Highlights & Side Effects. Trial Name: NCT05211843 — N/A

Drinking water (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05211843 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment for the trial open to octogenarians?

"This research is open to children aged between 5 and 10 years old."

Answered by AI

What is the scope of involvement in this experiment?

"Affirmative. Details on clinicaltrials.gov inform us that the trial is still searching for individuals to participate in it, with its initial posting occurring on October 12th 2022 and latest update being April 11th 2023. This study requires 120 volunteers from a single medical facility."

Answered by AI

Who is permitted to partake in this experiment?

"This trial seeks 120 children aged 5 to 10 years with a specific metabolomic profile. To qualify, the paediatric patient must have visited the UCSF Pediatric Dental Clinic for either an initial exam or recall and be sufficiently healthy to attend school; they also need to converse in English, Spanish, or Chinese and reside within San Francisco."

Answered by AI

Is this trial in the process of enrolling participants?

"Affirmative, according to clinicaltrials.gov the trial is currently recruiting. It was first published on December 10th 2022 and most recently updated April 11th 2023. The research demands 120 participants from one medical facility."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Saliva Insulin as Biomarker of Risk Factors for Metabolic Dysregulation and Caries

Jodi Stookey 2022. "Saliva Insulin as Biomarker of Risk Factors for Metabolic Dysregulation and Caries". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05211843.