Educational pamphlets for Cardiovascular Diseases

Phase-Based Estimates
1
Effectiveness
1
Safety
Duke University Medical Center, Durham, NC
Cardiovascular Diseases+2 More
Educational pamphlets - Other
Eligibility
18+
All Sexes
Eligible conditions
Cardiovascular Diseases

Study Summary

This study is evaluating whether a telephone-based educational curriculum can help improve cardiovascular disease related outcomes among HIV-infected clinic patients.

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Eligible Conditions

  • Cardiovascular Diseases
  • Human Immunodeficiency Virus (HIV) Infections
  • Cardiovascular Disease (CVD)

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Educational pamphlets will improve 2 primary outcomes and 2 secondary outcomes in patients with Cardiovascular Diseases. Measurement will happen over the course of baseline, 24 weeks, 48 weeks, 72 weeks.

Week 72
Change in 10-year atherosclerotic cardiovascular disease (ASCVD) risk score
Change in ambulatory systolic blood pressure
Change in fasting LDL-c levels
Total weight loss

Trial Safety

Safety Estimate

1 of 3

Trial Design

2 Treatment Groups

Educational pamphlets
Educational pamphlets + telephone

This trial requires 50 total participants across 2 different treatment groups

This trial involves 2 different treatments. Educational Pamphlets is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Educational pamphlets + telephone
Educational pamphlets
Other
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Telephone
2018
N/A
~2050

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 24 weeks, 48 weeks, 72 weeks
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly baseline, 24 weeks, 48 weeks, 72 weeks for reporting.

Closest Location

Duke University Medical Center - Durham, NC

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 5 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
In care at the Duke Infectious Diseases Clinic for HIV and for at least 24 months
On antiretroviral therapy
2013 American Heart Association 10-year ASCVD risk score ≥ 15%, with a diagnosis of either hypertension or hyperlipidemia
English literate (able to speak and read at a 6th grade level)
Subjects must have the capacity to give legally effective consent.

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What causes cardiovascular diseases?

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The cause of cardiovascular disease is influenced by multiple risk factors such as genetic predisposition, physiological factors, environmental factors, behaviours, and social and economic factors. This article explains the most influential risk factors for cardiovascular disease. Although there are many risk factors associated with cardiovascular diseases, some are treatable and preventable.

Unverified Answer

How many people get cardiovascular diseases a year in the United States?

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There are many kinds of cardiovascular disorders, with ischemia and atherosclerosis as two examples. There is a large number of cardiovascular disease patients each year in the United States, and more patients than ever before. While atherosclerotic heart disease is the most common cause of death in heart failure patients, there is a wide spectrum of patients suffering from ischemic heart disease, stroke, venous ulcers, atrial fibrillation, and a variety of other cardiovascular disorders.

Unverified Answer

What are the signs of cardiovascular diseases?

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The symptoms of vascular disorders are nonspecific. One group of symptoms consists in palpitations, fainting, breathlessness, weakness, fatigue, and chest pain when exercising. Other symptoms include pain on palpation of the abdomen, abdominal and/or back pain, irregular heartbeat, leg cramps and the feeling of fatigue. The presence of such symptoms should be assessed. The presence of the first symptoms of these diseases is suggestive of the diagnosis of vascular disorders. There are four signs that can be a first symptom of arteriosclerosis and heart disease: hypertension, elevated C-reactive protein, abnormal glucose levels, and dyslipidaemia.

Unverified Answer

Can cardiovascular diseases be cured?

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For the prevention of cardiovascular risk conditions, lifestyle modifications and use of medicines are necessary. However, in a population without diabetes or kidney disease, statin therapy can potentially prevent cardiovascular disease as long as the total cholesterol level is very low or moderately raised. The use of lipid-lowering medication might be necessary and statins should be used cautiously in women with familial hypercholesterolemia.

Unverified Answer

What are common treatments for cardiovascular diseases?

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The most common treatments are medications (e.g., antihypertensive drugs, vasodilators, etc.), physical therapy, nutrition education, and lifestyle education. Preventative measures must be taken in young adults since many people get cardiovascular diseases in their lifetime.

Unverified Answer

What is cardiovascular diseases?

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A cardiovascular disease is not a disease limited to the heart. It affects all the parts of the body, including the brain. The most common symptom of cardiovascular diseases is chest pain, particularly when it is referred from the left side of the chest of the heart, rather than being caused directly by the heart. Thus, there is no point in discussing and differentiating cardiovascular diseases, when they are simply called cardiovascular diseases. This is a symptom, rather than a disease. Therefore, cardiovascular disease is a syndrome like schizophrenia and tuberculosis. It is a problem, which a doctor can solve, rather than a patient. A patient is not a mere body object, but an end of a doctor's treatment.

Unverified Answer

Have there been any new discoveries for treating cardiovascular diseases?

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At present, there are not enough studies being done to say that some treatments are better or worse than others. The treatment of cardiovascular disease requires more research and clinical trials before being able to determine which treatments are the best.

Unverified Answer

What are the common side effects of educational pamphlets?

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The information on general side effects of pamphlets was generally well known, and most of the side effects were easily explained in the pamphlets. However, some side effects are easily explained in a way that other people are not familiar with.

Unverified Answer

How serious can cardiovascular diseases be?

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In a recent study, findings indicates a very low proportion of the patients with pre-existent cardiovascular diagnoses who were referred to a tertiary centre with coronary and/or vascular surgery for the treatment of life-threatening and debilitating cardiovascular diseases. We found that in only one third of patients with pre-existent cardiovascular diagnoses were cardiovascular surgery offered as treatment. Therefore, further efforts must be made to increase the proportion of patients with pre-existent cardiovascular diagnoses who are referred to tertiary cardiovascular surgical centres for the efficient treatment of life-threatening and debilitating cardiovascular diseases.

Unverified Answer

Has educational pamphlets proven to be more effective than a placebo?

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A single short story-driven educational pamphlet (compared with a control group) is no more effective in changing physicians' and patients' attitudes and beliefs toward secondary prevention of cardiovascular disease, or enhancing patients' beliefs, knowledge, or intentions to change secondary cardiovascular diseases risk factors.

Unverified Answer

What are the latest developments in educational pamphlets for therapeutic use?

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There were no differences between pamphlets from AOEI & CGE on key learning messages. The use of patient written information in cardiology outpatient clinics is not yet widespread despite recent improvements in practice standards in the UK.

Unverified Answer

Is educational pamphlets typically used in combination with any other treatments?

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Education plus active counseling for patients with a new diagnosis of CHF (EFPR) was associated with a significant increase in the likelihood of patients choosing to enroll in cardiac rehabilitation relative to the use of education alone. Patients with severe disease (New York Heart Association Class I/II) as well as patients with a longer length of index hospitalization had an increased likelihood of enrollment in cardiac rehabilitation when combined with active counseling relative to patients with mild disease or short index hospitalization.

Unverified Answer
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