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Behavioural Intervention

Aerobic Training for High Blood Pressure (BPVR Trial)

N/A

Recruiting

Led By Shane Phillips, PhD

Research Sponsored by University of Illinois at Chicago

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline (wk. 0), pre-training (wk. 8), post- training (wk. 16), post detraining (wk. 24)

Awards & highlights

BPVR Trial Summary

This trial will test the effects of aerobic and resistance training on arterial stiffness, FMD, and gluteal adipose tissue in sedentary, overweight/obese women.

Eligible Conditions

High Blood Pressure
Vascular Disease
Cardiovascular Disease

BPVR Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline (wk. 0), pre-training (wk. 8), post- training (wk. 16), post detraining (wk. 24)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline (wk. 0), pre-training (wk. 8), post- training (wk. 16), post detraining (wk. 24)

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (wk. 0), pre-training (wk. 8), post- training (wk. 16), post detraining (wk. 24) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Changes in peripheral and central blood pressure

Secondary outcome measures

Changes in arterial stiffness

Changes in endothelial function

BPVR Trial Design

2Treatment groups

Experimental Treatment

Group I: Resistance TrainingExperimental Treatment1 Intervention

Participants will undergo a supervised resistance training program in accordance with established guidelines. Each session will be monitored by a physical therapist or exercise physiologist. Sessions will be carried out 3 times per week, 45 min per session. Muscle strength will be determined once before and once after resistance training by measuring ten repetition maximum (10 RM) for each exercise. Eight exercises (three sets; 8-12 repetitions) will be used on each of the large muscle groups (leg press, leg extension, leg curl, chest press, shoulder extension, biceps curl, abdominal crunch and back extension). In addition, workloads will be progressively increased if the patients can lift the weight more than 12 repetitions.

Group II: Aerobic TrainingExperimental Treatment1 Intervention

Participants will undergo a supervised endurance training program in accordance with established guidelines. Each session will be monitored by a physical therapist or exercise physiologist. Sessions will be carried out 3 times per week. During each session, participants will complete a 5 min warm-up followed by 30-45 min of endurance exercise using cycle ergometry. Intensity will be monitored using heart rate monitors during each exercise session, and each participant will receive an exercise prescription with a heart range equivalent to 65-85% of their heart rate max. Participants will be asked to complete 30 min of exercise during each session in week 1, 35 min in week 2 and 40-45 min weeks 3-8 with a 5 min cool down period.

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Who is running the clinical trial?

University of Illinois at ChicagoLead Sponsor

607 Previous Clinical Trials

1,559,215 Total Patients Enrolled

National Heart, Lung, and Blood Institute (NHLBI)NIH

3,834 Previous Clinical Trials

47,310,495 Total Patients Enrolled

Shane Phillips, PhD4.749 ReviewsPrincipal Investigator - University of Illinois at Chicago

Medical School - University of North Texas

John Peter Smith Hospital, Residency in Family Medicine

5Patient Review

This was an excellent experience. I felt well-informed and like something was actually accomplished.

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there a possibility to join this research project at the present time?

"Affirmative. As of today, the clinical trial hosted on clinicaltrials.gov is actively seeking enrolment from potential patients. The original posting dates back to October 1st 2016 and was recently updated at the end of October 2022; with 140 participants being recruited for one site."

Answered by AI

What is the upper limit for participants in this experiment?

"Yes, the records on clinicaltrials.gov verify that this medical investigation is currently recruiting individuals for participation. This study was first posted to the website on October 1st 2016 and has been most recently amended as of October 31st 2022. The trial requires 140 subjects at a single site."

Answered by AI

Are elderly individuals being accepted as participants in this research project?

"Individuals aged 18 to 55 are eligible to enter this clinical trial."

Answered by AI

What are the criteria for individuals to be eligible for this investigation?

"This medical research is recruiting 140 individuals, aged 18-55 and suffering from hypertension. Furthermore, they must meet the following conditions: Sedentary lifestyle; BMI between 18.5 to 40 kg/m²; having two African-American or Caucasian non-Hispanic parents who were born in the United States of America."

Answered by AI