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Short-Term Exercise for Cardiovascular Health (EPC-Ex Trial)

N/A

Waitlist Available

Led By Steven J Prior, Ph.D.

Research Sponsored by Baltimore VA Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up day 15

Awards & highlights

EPC-Ex Trial Summary

This trial will study the effects of exercise on endothelial progenitor cells (EPCs), which are important for maintaining cardiovascular health. Older adults who are endurance-trained athletes and sedentary individuals will be compared. The investigators hypothesize that older endurance-trained athletes will have better EPC function than sedentary individuals, and that altering the physical activity levels of both groups will move them to intermediate points between these two extremes.

Who is the study for?

This trial is for non-smoking individuals aged 50-80, including postmenopausal women, with a BMI of 18-35. It's not suitable for those with a history of cancer, HIV, uncontrolled blood fats or high blood pressure, diabetes, liver disease, heart/stroke issues, or kidney disease.Check my eligibility

What is being tested?

The study examines how short-term exercise affects cells called Endothelial Progenitor Cells (EPCs), which help keep the cardiovascular system healthy. The trial will compare older athletes and sedentary people to see if changes in activity levels influence these cells.See study design

What are the potential side effects?

Since this trial involves exercise as an intervention rather than medication, side effects are minimal but may include typical exercise-related discomfort such as muscle soreness or fatigue.

EPC-Ex Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ day 15

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~day 15

This trial's timeline: 3 weeks for screening, Varies for treatment, and day 15 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Baseline Endothelial progenitor cell number

Final Endothelial Progenitor Cell Number

Secondary outcome measures

Baseline Endothelial Reactivity

Final Endothelial Reactivity

EPC-Ex Trial Design

2Treatment groups

Experimental Treatment

Group I: Sedentary Older AdultsExperimental Treatment1 Intervention

Group II: Older Endurance AthletesExperimental Treatment1 Intervention

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Baltimore VA Medical CenterLead Sponsor

32 Previous Clinical Trials

3,065 Total Patients Enrolled

1 Trials studying Aging

30 Patients Enrolled for Aging

University of Maryland, College ParkOTHER

155 Previous Clinical Trials

45,605 Total Patients Enrolled

5 Trials studying Aging

546 Patients Enrolled for Aging

University of Maryland, BaltimoreOTHER

687 Previous Clinical Trials

374,586 Total Patients Enrolled

5 Trials studying Aging

231 Patients Enrolled for Aging

Media Library

Exercise Clinical Trial Eligibility Overview. Trial Name: NCT01169831 — N/A

Aging Research Study Groups: Older Endurance Athletes, Sedentary Older Adults

Aging Clinical Trial 2023: Exercise Highlights & Side Effects. Trial Name: NCT01169831 — N/A

Exercise 2023 Treatment Timeline for Medical Study. Trial Name: NCT01169831 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

If a person is more than 20 years old, can they participate in this research study?

"This particular trial is for patients aged 50-80. However, there are 41 studies currently underway for people under 18 and 692 for those over 65."

Answered by AI

What are the qualifying factors for this clinical trial?

"The cardiovascular disease clinical trial has room for 60 people aged 50-80."

Answered by AI

Can patients sign up for this treatment option at this time?

"Unfortunately, this particular study is no longer recruiting patients according to the information found on clinicaltrials.gov. This trial was originally posted on 7/1/2011 but was last updated on 2/28/2022. There are however, 785 other trials that are still looking for participants."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Regulation of Endothelial Progenitor Cells by Short-Term Exercise

Steven J. Prior, Ph.D. 2011. "Regulation of Endothelial Progenitor Cells by Short-Term Exercise". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01169831.