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Statin Prescribing Intervention for HIV/AIDS Patients (INSPIRE Trial)

N/A

Waitlist Available

Led By Allison Diamant, MD, MSHS

Research Sponsored by University of California, Los Angeles

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

History of heart attack, stroke, or peripheral vascular disease

Diagnosed with HIV

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 months

Awards & highlights

INSPIRE Trial Summary

This trial will test a multi-level intervention designed to increase statin prescribing for people with HIV, which could reduce their risk of cardiovascular disease.

Who is the study for?

This trial is for people aged 40 or older with HIV who are at higher risk of heart disease, either because they have high LDL cholesterol, diabetes with LDL over 70, a history of heart issues like attacks or strokes, or an estimated cardiovascular risk above 7.5% in the next ten years. Physicians caring for HIV patients can also participate.Check my eligibility

What is being tested?

The study tests a new approach to encourage doctors to prescribe statins more often to HIV patients at risk of heart disease. It includes special education programs and feedback based on behavioral economics principles.See study design

What are the potential side effects?

Since this trial focuses on educational interventions and provider feedback rather than direct medical treatments, there are no direct side effects from medications being tested.

INSPIRE Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have had a heart attack, stroke, or issues with blood flow in my limbs.

Select...

I have been diagnosed with HIV.

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My LDL cholesterol is high, and I have diabetes.

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I am 40 years old or older.

INSPIRE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in proportion of PLWH with cardiovascular risk factors seen by a physician receiving statin therapy

INSPIRE Trial Design

3Treatment groups

Experimental Treatment

Group I: Provider LevelExperimental Treatment3 Interventions

Group II: Patient LevelExperimental Treatment1 Intervention

Group III: Organization LevelExperimental Treatment1 Intervention

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Knowledge assessment

2009

N/A

~80

Education Intervention

2023

Completed Phase 3

~3310

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor

1,526 Previous Clinical Trials

10,275,829 Total Patients Enrolled

RANDOTHER

137 Previous Clinical Trials

510,176 Total Patients Enrolled

Olive View-UCLA Education & Research InstituteOTHER

33 Previous Clinical Trials

879,939 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the geographic sites in which this experiment is being conducted?

"Currently, 8 medical facilities are providing this clinical trial including Tarzana Treatment Centers, Inc. in Tarzana, Watts Health Center in Lancaster and Antelope Valley Health Center in Commerce with additional sites located across the country."

Answered by AI

Is this research study currently enlisting participants?

"The clinicaltrials.gov website indicates that, while originally posted on March 4th 2019 and last updated on January 6th 2022, this medical trial is currently not taking in new patients. However, there are still a plethora of trials actively searching for participants with 654 other studies presently recruiting people to join their research."

Answered by AI

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