115 Participants Needed

Preoperative Breast MRI for Breast Cancer

Recruiting at 3 trial locations
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Memorial Sloan Kettering Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 1 JurisdictionThis treatment is already approved in other countries

Trial Summary

What is the purpose of this trial?

Breast MRI is a fairly new technology, but it has been well studied. It is now used routinely in many patients with breast cancer. It has been shown to be useful in detecting areas of cancer that cannot be seen using other types of scans or tests.The purpose of this study is to see how often MRI can find other areas of cancer in women with one area of breast cancer, and to determine how having the MRI test affects their treatment. The purpose is also to study any areas of abnormality seen on your MRI with special methods that allow the images of your breast tissue and the microscopic analysis of your breast tissue to be compared very carefully. The study also aims to follow women who enter the study over a 10-year period to determine how often the breast cancer comes back.

Research Team

KV

Kimberly Van Zee, MD

Principal Investigator

Memorial Sloan Kettering Cancer Center

Eligibility Criteria

This trial is for women under 60 with a specific breast cancer diagnosis (DCIS or DCIS with microinvasion) who haven't had certain biopsies or surgeries yet. They must be able to have breast surgery at MSKCC and not be pregnant, nursing, or have conditions that make MRI unsafe like pacemakers, metal implants, severe weight over 350 lb., allergies to MRI contrast agents, or metal in the eye.

Inclusion Criteria

I am under 60 years old.
My breast surgery will be done at MSKCC.
I am female.
See 3 more

Exclusion Criteria

I am 60 years old or older.
I cannot have breast-saving surgery due to my condition.
I had a surgical biopsy for DCIS or DCIS with slight invasion before joining.
See 2 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Preoperative MRI Assessment

Participants undergo MRI to detect additional areas of cancer and assess treatment impact

1-2 weeks
1 visit (in-person)

Surgical Intervention

Participants undergo planned surgical intervention based on MRI findings

1 week
1 visit (in-person)

Follow-up

Participants are monitored for recurrence of breast cancer over a 10-year period

10 years

Treatment Details

Interventions

  • MRI
Trial Overview The study tests how effective Breast MRI is in detecting additional cancer areas in women already diagnosed with one area of breast cancer. It examines if the MRI influences treatment decisions and compares image findings with microscopic tissue analysis. Participants will also be followed for ten years to monitor cancer recurrence.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: 1Experimental Treatment1 Intervention
Women with core biopsy proven DCIS with or without microinvasion seen for surgical consultation at Memorial Sloan-Kettering Cancer Center and for whom operative intervention is planned.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Memorial Sloan Kettering Cancer Center

Lead Sponsor

Trials
1,998
Recruited
602,000+
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Terms of Service·Privacy Policy·Cookies·Security