ACL and ALL Reconstruction vs ACL Alone for Anterior Cruciate Ligament Injury
(PALLET Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The overall aim of this multicenter RCT is to determine whether concomitant ALL reconstruction in children undergoing and ACL reconstruction will longitudinally result in a lower rate of graft failure than ACL reconstruction alone.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Is ACL and ALL reconstruction safe for humans?
How does ACL and ALL reconstruction differ from ACL reconstruction alone for knee injuries?
What data supports the effectiveness of the treatment ACL and ALL Reconstruction vs ACL Alone for Anterior Cruciate Ligament Injury?
Who Is on the Research Team?
Neeraj Patel, MD
Principal Investigator
Lurie Children's Hospital
Are You a Good Fit for This Trial?
This trial is for children under 18 who need their first ACL (knee ligament) reconstruction surgery within 6 months of injury, using their own tissue. It's not for those with previous knee injuries/surgeries, neuromuscular disorders affecting the knee, or anyone needing more complex knee procedures.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo ACL reconstruction surgery, with or without concomitant ALL reconstruction
Follow-up
Participants are monitored for safety, complications, and effectiveness of the surgery
What Are the Treatments Tested in This Trial?
Interventions
- ACL Reconstruction
- ALL Reconstruction
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ann & Robert H Lurie Children's Hospital of Chicago
Lead Sponsor
UCSF Benioff Children's Hospital - San Francisco
Collaborator
Texas Children's
Collaborator
Children's Hospital of Philadelphia
Collaborator