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AZD6244 + Chemotherapy for Advanced Cancer
Study Summary
This trial is testing a new drug in combination with standard chemotherapies to see if it is safe and effective for treating advanced solid tumors.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2020 Phase 2 trial • 334 Patients • NCT01248247Trial Design
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Who is running the clinical trial?
Media Library
- My cancer can't be cured with surgery or radiation, and chemotherapy is the standard treatment for me.I can carry out all my usual activities without help.I have been treated with a MEK inhibitor before.I can swallow capsules.My brain or spinal cord cancer has been treated, is stable for 1 month, and I'm not on steroids.
- Group 1: 1
- Group 2: 2
- Group 3: 3
- Group 4: 4
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many distinct venues is the clinical testing available in?
"Currently, 4 medical sites are actively running this trial. They can be found in Nashville, Detroit and Houston with an additional four other locations available. To reduce any necessary travel arrangements, it is advised to select the site closest to you if one decides to participate."
What criteria must a person meet to be considered for enrolment into this experiment?
"To be considered for this trial, applicants ought to have malignant colorectal tumors and span the age range of 18-130. A maximum of 140 people will ultimately be selected."
What therapeutic purposes is AZD6244 typically employed for?
"AZD6244 has been developed to treat metastatic bladder cancer, as well as various other diseases such as advance directives, small cell lung cancer (SCLC), lymphoma, and Hodgkins."
Is the age criterion for this experiment limited to those younger than 25 years?
"As stated in the inclusion criteria for this clinical trial, participants must be aged between 18 and 130."
How hazardous is AZD6244 for patients who take it?
"AZD6244 has not yet been extensively tested, so its safety rating was set at 1 on our risk scale. This is a Phase 1 trial which implies that there is limited data available to support both efficacy and security."
What further exploration has been conducted regarding AZD6244?
"Presently, there are 147 phase 3 clinical trials being conducted for AZD6244 in 440 active studies. Of these sites, the majority of them can be found in Fuzhou, Fujian Province; however, 30211 centers across the world have been enlisted to partake within this research endeavour."
What is the maximal number of participants being enrolled in this trial?
"Unfortunately, enrollment for this trial has been closed. This clinical study was originally posted on December 14th 2007 and the most recent update was made September 20st 2022. If you are seeking other trials to enroll in, there are 6280 studies involving colon neoplasms with participants being recruited and 440 trials recruiting patients taking AZD6244."
Are there any current opportunities to enroll in this investigation?
"Per the clinicaltrials.gov registry, this trial is no longer recruiting new participants; it was initially posted on December 14th 2007 and its most recent update came in September 20th 2022. Despite that, over 6720 other medical studies are currently open for enrollment."
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