Mobile TMS for Depression

(TMS Trial)

Overseen By Alexandra Herron, BA

Age: 18+

Sex: Any

Trial Phase: Phase 4

Sponsor: Medical University of South Carolina

Disqualifiers: Unstable conditions, Seizures, Pregnant, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Prior Safety Data This treatment has passed at least one previous human trial

Compensation: Varies

Number of Visits: 5

Duration: 1-2 weeks

30 Participants Needed

Trial Summary

What is the purpose of this trial?

In this pilot study, investigators propose to design and create a portable TMS unit, in a van, and then test out delivering TMS in three different locations in South Carolina, all affiliated with MUSC and within 2-hours driving from Charleston, SC. This study would test out this new delivery mode, and provide valuable feasibility, safety, and efficacy lessons for later refinement and potential widespread adoption of mobile TMS as a treatment option, both in our state and across the US.

Research Team

Mark George, MD

Principal Investigator

Medical University of South Carolina

Eligibility Criteria

This trial is for adults aged 22-80 with treatment-resistant depression, who can communicate in English and provide consent. Participants must have access to a computer with videoconferencing for initial screening. It's not specified who cannot join the trial.

Inclusion Criteria

I am between 22 and 80 years old.

I can read and communicate in English.

I can make my own medical decisions.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive FDA approved accelerated TMS (6 sessions each day, over 2 hours, for 5 days, spread over one or two weeks)

1-2 weeks

Daily visits for 5 days

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 week

Treatment Details

Interventions

• Mobile Transcranial Magnetic Stimulation

Trial Overview The study is testing a new way of delivering Transcranial Magnetic Stimulation (TMS) using a portable unit inside a van at different locations in South Carolina. The goal is to assess how feasible, safe, and effective mobile TMS could be as a widespread treatment option.

Participant Groups

Group I: Open label Clinical TMS for Depression Experimental Treatment 2 Interventions

This will be FDA approved Left Prefrontal TMS for treating depression, we will be performing this within a VA, located at clinics throughout SC.

Who Is Running the Clinical Trial?

Medical University of South Carolina

Lead Sponsor

Trials

994

Recruited

7,408,000+