Physical Activity Program for Cancer Survivors
(CICI-PA Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to evaluate how a new physical activity program can assist cancer survivors experiencing "chemo-brain" (memory and thinking problems after chemotherapy). Based on Social Cognitive Theory and delivered through technology, the program uses smartphone apps to guide exercise and health education and includes a Fitbit for tracking activity. The trial will compare cancer survivors with type 2 diabetes to those without, to understand differences in brain and heart health. Suitable candidates for this trial are cancer survivors who underwent chemotherapy in the last three years, are experiencing memory issues, and own a smartphone or computer with internet access. Participants should be prepared to join a 12-week exercise program delivered remotely. As an unphased trial, this study offers a unique opportunity for participants to contribute to innovative research that could enhance the quality of life for cancer survivors.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you have Type 2 diabetes, you may continue using medications to treat hyperglycemia (high blood sugar).
What prior data suggests that this physical activity program is safe for cancer survivors?
Research has shown that programs based on social cognitive theory, like the one in this trial, are effective and safe for cancer survivors. One study found that using electronic devices and wearable technology to encourage physical activity was practical and well-received. These programs often help people become more active without causing major side effects.
Other studies on similar technology-based activity programs have also demonstrated positive outcomes. Participants typically experience improvements in their physical and mental health without serious negative effects. This suggests that the treatment in this trial is likely safe for participants.12345Why are researchers excited about this trial?
Researchers are excited about the Social Cognitive Theory-based, Technology-delivered Physical Activity Program for cancer survivors because it offers a personalized approach to improving health outcomes. Unlike traditional physical therapy or group exercise classes, this program uses smartphone apps to deliver highly personalized aerobic and muscle-strengthening exercises remotely. By employing tools like Fitbit for activity tracking and resistance bands for strength training, the program makes it easy for participants to engage in physical activity from anywhere. Additionally, the emphasis on health education, goal setting, and self-monitoring through journaling aims to enhance both physiological and psychological well-being, providing a holistic approach to recovery.
What evidence suggests that this physical activity program is effective for cancer survivors?
Research shows that physical activity can improve the quality of life for cancer survivors. In this trial, participants will engage in a Social Cognitive Theory-based, technology-delivered physical activity program. Similar programs have increased activity levels and improved health outcomes. Specifically, the ENRICH trial found that these programs helped cancer survivors become more active. Personalized exercise plans can lead to better results by focusing on what works best for each person. These programs have improved various health aspects, including reducing inflammation and enhancing brain function, which are important for addressing "chemo-brain." Overall, evidence suggests that participating in a structured physical activity program benefits cancer survivors.23567
Who Is on the Research Team?
Zachary C Pope, PhD
Principal Investigator
University of Oklahoma Health Sciences
Mikhail Kellawan, PhD
Principal Investigator
University of Oklahoma, Department of Health and Exercise Science
Andriy Yabluchanskiy, MD, PhD
Principal Investigator
University of Oklahoma Health Sciences
Are You a Good Fit for This Trial?
This trial is for adults over 18 who've had non-CNS cancer treatment with chemotherapy in the last three years and are experiencing 'chemo-brain'. It includes those with Type 2 Diabetes (T2D) and without. Participants must speak/read English, give informed consent, own a smartphone/computer with internet, and be willing to join a 12-week remote physical activity program.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Initial assessments of cerebrovascular, cognitive, pro-inflammatory, and cardiometabolic outcomes
Treatment
Participants engage in a 12-week technology-delivered physical activity program
Follow-up
Participants are monitored for changes in health outcomes post-treatment
What Are the Treatments Tested in This Trial?
Interventions
- Social Cognitive Theory-based, Technology-delivered Physical Activity Program
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Oklahoma
Lead Sponsor