Pink and Pearl Campaign for Lung Cancer

Overseen By Beryne Odeny, M.D., MPH, Ph.D.

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Washington University School of Medicine

Disqualifiers: Lung cancer, Hemoptysis, Unexplained weight loss, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 7

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if a campaign can increase lung cancer screenings for women during mammogram visits. It will assess whether the campaign results in more referrals and quicker screenings for those who might need them. The trial will also examine factors that facilitate or hinder access to these screenings. Women undergoing mammograms at Christian Hospital with a history of smoking may be suitable candidates for this study. As an unphased trial, this study provides a unique opportunity to contribute to research that could enhance cancer screening processes for women.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that the Pink and Pearl Campaign is safe for promoting lung cancer screening?

Research has shown that the Pink and Pearl Campaign is dedicated to raising awareness and encouraging screenings for breast and lung cancer. The goal is to detect cancer early, which can simplify treatment or offer more options.

This is an awareness campaign, not a medical treatment, and focuses on educating and organizing efforts to promote screenings. No medications or medical procedures are involved in the campaign itself, so there are no direct safety concerns. The campaign guides women to established and safe screenings when conducted according to medical guidelines.

Participants receive support from nurse navigators who assist with referrals to primary care, ensuring a smooth and informed process for lung cancer screening. The campaign aims to increase screening rates, not introduce new treatments, so it does not have any adverse effects. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Pink and Pearl Campaign for lung cancer screening because it takes an innovative approach by integrating lung cancer screening eligibility checks into routine breast cancer screening appointments. This method leverages the existing infrastructure of mammography appointments to identify women who might benefit from lung cancer screenings, potentially increasing early detection rates. Unlike traditional lung cancer screenings that require separate appointments, this campaign aims to streamline the process, making it more convenient for patients. By involving mammography technicians and nurse navigators to facilitate referrals, the campaign could significantly enhance the accessibility and uptake of lung cancer screenings.

What evidence suggests that the Pink and Pearl Campaign is effective for improving lung cancer screening uptake?

Research has shown that the Pink and Pearl Campaign, which participants in this trial may experience, has increased lung cancer screenings by raising awareness. In Tennessee, this campaign successfully promoted both breast and lung cancer screenings, resulting in higher participation. Other studies have found that nurse guides and clear referral systems boost the likelihood of eligible women completing lung cancer screenings. By employing these strategies, the campaign has achieved positive results in early cancer detection. Overall, the Pink and Pearl Campaign effectively encourages more women to undergo lung cancer screenings. ^{2 4 6 7 8}

Who Is on the Research Team?

Beryne Odeny, M.D., MPH, Ph.D.

Principal Investigator

Washington University School of Medicine

Are You a Good Fit for This Trial?

This trial is for women eligible for lung cancer screening who are undergoing mammography at Christian Hospital. It aims to assess if the Pink & Pearl Campaign, which promotes awareness and referral for lung cancer screening, effectively increases screenings.

Inclusion Criteria

I am ready and able to undergo treatment for lung cancer if diagnosed.

Able to understand and willing to sign an IRB-approved written informed consent document

Undergoing screening mammography at Christian Hospital

Exclusion Criteria

I don't have a serious health issue that could shorten my life.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

1 visit (in-person)

Implementation

Implementation of the Pink & Pearl Campaign to promote awareness, referral, and completion of lung cancer screening among eligible women

6 months

Ongoing visits as part of routine mammography

Follow-up

Participants are monitored for the completion of lung cancer screening and the effectiveness of the campaign

6 months

Follow-up assessments at 6 months

What Are the Treatments Tested in This Trial?

Interventions

• Pink and Pearl Campaign

Trial Overview The effectiveness of the Pink & Pearl Campaign in increasing lung cancer screening referrals and completion rates among eligible women is being tested. The study uses a mixed methods design to evaluate individual and health system factors influencing uptake.

How Is the Trial Designed?

Group I: Participants - scheduled for mammography and eligible for LCS Experimental Treatment 1 Intervention

All women coming in for breast cancer screening will be assessed for LCS eligibility using a screening questionnaire administered by mammography technicians. Patients who are determined to be eligible for LCS will be asked by the mammography technician if they will opt into being contacted by the nurse navigator, who will facilitate their referral to primary care to schedule a LCS appointment at Siteman Cancer Center.

Group II: Providers Active Control 1 Intervention

Providers in the breast radiology service who referred women to LCS. Investigators will gather information on the feasibility, acceptability, and appropriateness of the Pink and Pearl project.

Who Is Running the Clinical Trial?

Washington University School of Medicine

Lead Sponsor

Trials

2,027

Recruited

2,353,000+

Citations

1. clinicaltrials.gov clinicaltrials.gov/study/NCT07146568

Study Details | NCT07146568 | Evaluating the ... The purpose of this study is to evaluate the effectiveness of the Pink & Pearl Campaign in improving LCS uptake among LCS-eligible women ...

2. jto.org jto.org/article/S1556-0864(24)01112-2/fulltext

MA18.12 Innovations in Lung Cancer Screening Tennessee's Department of Health launched the first Pink and Pearl Campaign to raise awareness for breast and lung cancer screening, simultaneously. Building ...

3. rush.edu rush.edu/pink-and-pearl-campaign-enhancing-early-detection-lung-cancer-rush

Pink and Pearl Campaign: Enhancing Early Detection ... Learn about the Pink and Pearl Campaign at Rush, which works to enhance early detection of lung cancer.

4. sciencedirect.com sciencedirect.com/science/article/pii/S1556086424011122

MA18.12 Innovations in Lung Cancer Screening Tennessee's Department of Health launched the first Pink and Pearl Campaign to raise awareness for breast and lung cancer screening, simultaneously. Building ...

5. clinicaltrials.gov clinicaltrials.gov/study/NCT06898333

Implementation and Effectiveness of the BJC-Pink ... These implementation outcomes will help identify whether the campaign was put in place successfully or not. This proposal will inform strategies for integrating ...

6. tn.gov tn.gov/health/health-program-areas/fhw/get-involved-with-fhw/health-campaigns/pink-and-pearl-campaign.html

Pink and Pearl Campaign Screening can detect cancer early before symptoms appear. An early diagnosis may mean the cancer is easier to treat or that more treatment options may be ...

7. edhub.ama-assn.org edhub.ama-assn.org/acr-lifelong-learning/module/2829401

Pink & Pearl Campaign: Healthcare Professional Information ... This video was created to educate Healthcare Professionals on the Pink & Pearl Campaign, a collaborative effort to promote Breast and Lung Cancer Awareness.

8. acr.org acr.org/Clinical-Resources/Clinical-Tools-and-Reference/Screening-Resources/lung-cancer-resources

Lung Cancer Screening Resources Your best resource for safe, effective lung cancer screening with the latest research, toolkits and key patient information.