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Intra-operative Magnetic Resonance Imaging (MRI) for Breast Cancer

N/A

Waitlist Available

Led By Thanh Barbie, MD

Research Sponsored by Dana-Farber Cancer Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 years

Awards & highlights

Study Summary

This trial is testing whether MRI and MS can be used during surgery to help guide breast cancer removal.

Eligible Conditions

Breast Cancer

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Magnetic Resonance Imaging

Secondary outcome measures

To determine the operating characteristics (sensitivity, specificity, negative predictive value and positive predictive value) of MRI in detecting tumor boundaries as confirmed with pathologic results

To develop novel image processing algorithms to detect remnant tumor from intraoperative DCE-MRI in presence of tissue edema and reduced perfusion

To evaluate the correlation of intraoperative mass spectrometry results to tumor boundaries as confirmed with pathologic results.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Intra-operative Magnetic Resonance Imaging (MRI)Experimental Treatment2 Interventions

Preoperative diagnostic MRI Intra-operative MRI Standard lumpectomy and sentinel node biopsy if indicated, or standard axillary dissection if clinically indicated Specimen to Pathology and Mass Spectrometer (Analysis of Tissue Sample)

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Intra-operative Magnetic Resonance Imaging (MRI)

2015

N/A

~40

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Dana-Farber Cancer InstituteLead Sponsor

1,079 Previous Clinical Trials

340,908 Total Patients Enrolled

142 Trials studying Breast Cancer

22,617 Patients Enrolled for Breast Cancer

Thanh Barbie, MD5.03 ReviewsPrincipal Investigator - Dana-Farber Cancer Institute

Dana-Farber Cancer Institute

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are the age restrictions of this scientific investigation limited to individuals below 30 years old?

"The requirements to be included in this research is that candidates must fall between the ages of 18 and 75. Separately, 64 studies are available for minors while 2208 trials target elderly participants."

Answered by AI

What is the current capacity of this clinical investigation?

"Affirmative. Clinicaltrials.gov data confirms that this clinical investigation, which was initially published on February 1st 2015, is presently recruiting participants. Approximately 43 people need to be enrolled from 2 distinct healthcare facilities."

Answered by AI

May I submit an application to become a participant in this research endeavor?

"These requirements must be met to partake in the clinical trial: breast cancer, 18-75 years old. The study is aiming for 43 individuals in total."

Answered by AI

Is the program currently open to new participants?

"Indeed, the information posted on clinicaltrials.gov shows that this trial is actively seeking participants. It was initially published on February 1st 2015 and last modified on January 24th 2022 with a goal of enrolling 43 patients from 2 different sites."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Evaluating Mass Spectrometry And Intraoperative MRI In The Advanced Multimodality Image Guided Operating Suite (Amigo) In Breast-Conserving Therapy

Thanh Barbie, MD 2015. "Evaluating Mass Spectrometry And Intraoperative MRI In The Advanced Multimodality Image Guided Operating Suite (Amigo) In Breast-Conserving Therapy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02335671.