72 Participants Needed

Survivors Journey+ for Brain Tumor

(SJ Trial)

Recruiting at 1 trial location
SL
Overseen ByShari L Wade, PhD
Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: Children's Hospital Medical Center, Cincinnati
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests an online program called "Survivor's Journey+" to help teens and young adults who have survived pediatric brain tumors, along with their caregivers, better manage daily challenges. The trial compares the program's effectiveness with a set of internet resources designed for these survivors and their families. Participants will be randomly assigned to either use the Survivor's Journey+ program with weekly coaching or access general internet resources. Those who completed tumor treatment over a year ago and live with a parent or guardian may be a good fit.

As an unphased trial, this study offers a unique opportunity to contribute to research that could improve support for survivors and their families.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It seems to focus on an online program rather than medication changes.

What prior data suggests that the Survivors Journey+ program is safe for teens and young adults?

Research has shown that the Survivors Journey+ (SJ+) program is safe for participants. Previous studies have examined the use of online problem-solving therapy to enhance the quality of life for children who have survived brain tumors. These studies suggest that the treatment is well-tolerated, with no major safety issues reported.

Although specific data on side effects is not available, the program's focus on teaching skills like problem-solving and coping indicates it is low-risk. Its design as an online coaching program, typically non-invasive, further supports this. The SJ+ program aims to improve well-being without using medications or physical treatments.12345

Why are researchers excited about this trial?

Researchers are excited about the Survivor's Journey+ program because it takes a comprehensive approach to improving the quality of life for brain tumor survivors, particularly adolescents and emerging adults. Unlike standard treatments, which often focus solely on the medical aspects, this program addresses the mental and emotional challenges survivors face by teaching stress management, problem-solving, and communication skills. Additionally, it is tailored specifically to the unique developmental needs of young survivors and their families, aiming to enhance their overall well-being and readiness for life's challenges. This holistic approach is what sets it apart from existing options, making it a promising addition to survivorship care.

What evidence suggests that this trial's treatments could be effective for pediatric brain tumor survivors?

Research has shown that the "Survivor's Journey+" (SJ+) program, which participants in this trial may receive, might improve the quality of life for children who have survived brain tumors. Studies have found that online programs like SJ+ can facilitate access to the emotional and mental support needed for well-being. Early results suggest these programs aid in problem-solving, coping with challenges, and enhancing overall well-being. This is crucial for young survivors who encounter unique difficulties after treatment. While more information is needed, the program rests on a strong foundation that promises positive changes for participants. Another group in this trial will receive access to Internet Resources Comparison (IRC), which offers a homepage of pediatric brain tumor survivor resources and links, ensuring both groups have equal access to information and resources available online.12678

Who Is on the Research Team?

SL

Shari L Wade, PhD

Principal Investigator

Children's Hospital Medical Center, Cincinnati

Are You a Good Fit for This Trial?

This trial is for teens and young adults aged 15-25 who have survived a pediatric brain tumor, as well as their caregivers. They should be willing to engage with an online program and participate in assessments over time. Specific details on exclusion criteria are not provided.

Inclusion Criteria

Lives with parent/guardian(s)
English is the main language spoken in my home.
My last cancer treatment was over a year ago.
See 1 more

Exclusion Criteria

History of psychiatric hospitalization
Resides outside of the family home
English is not the main language spoken in my home.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive access to the Survivors Journey+ (SJ+) program or Internet Resources Comparison (IRC) with weekly online coaching sessions for approximately 3 months

12 weeks
Weekly online sessions

Follow-up

Participants are monitored for outcomes such as quality of life, internalizing symptoms, and executive function skills at 6 months post-baseline

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • Survivor's Journey+

Trial Overview

The 'Survivors Journey+' (SJ+) online program is being tested to see if it helps improve the wellbeing of Pediatric Brain Tumor Survivors (PBTS) and their caregivers by teaching problem-solving and coping skills. Participants will either use SJ+ with coaching or access internet resources, with outcomes measured up to six months post-baseline.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Survivors Journey ProgramExperimental Treatment1 Intervention
Group II: Internet Resources ComparisonExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Children's Hospital Medical Center, Cincinnati

Lead Sponsor

Trials
844
Recruited
6,566,000+

Nationwide Children's Hospital

Collaborator

Trials
354
Recruited
5,228,000+

Citations

Study Details | NCT07321353 | Survivors Journey+

These outcomes include quality of life, internalizing symptoms, performance-based executive function skills, depression, and family impact.

2.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/31724307/

A Survivor's Journey: Preliminary efficacy of an online ...

Online interventions such as Survivor's Journey may decrease barriers to evidence-based psychosocial care for brain tumor survivors.

A Survivor's Journey: Preliminary efficacy of an ...

Online interventions such as Survivor's Journey may decrease barriers to evidence-based psychosocial care for brain tumor survivors.

Social challenges and isolation in pediatric brain tumor ...

Recent advances in surgical techniques, radiation, and chemotherapy have significantly improved survival outcomes for pediatric brain tumor survivors (PBTS), ...

Development of a Web-Based Psychosocial Intervention ...

Purpose: To develop A Survivor's Journey, a web-based psychosocial intervention for adolescent and young adult (AYA) survivors of pediatric brain tumors (PBTs) ...

Survivors Journey+ for Brain Tumor (SJ Trial)

Participants will either use SJ+ with coaching or access internet resources, with outcomes measured up to six months post-baseline. How Is the Trial Designed? 2.

Survivors Of Pediatric Brain Tumors: Psychosocial Outcomes ...

Psychological outcomes in long-term survivors of childhood brain cancer: A report from the childhood cancer survivor study. Journal of Clinical Oncology, 22 ...

Neurobehavioral Impairment in Pediatric Brain Tumor ...

This meta-analysis found that PBTS are at higher risk of attention problems, emotional difficulties and psychosocial problems compared to the healthy ...