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MRI Technique

Validation of rCBV accuracy for Brain Tumor

N/A
Waitlist Available
Led By C C Quarles, PhD
Research Sponsored by St. Joseph's Hospital and Medical Center, Phoenix
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up within 60 days of mri
Awards & highlights

Study Summary

This trial is looking at using MRI to better assess brain tumors, with the goal of improving diagnosis, localization, and treatment response assessment.

Eligible Conditions
  • Brain Tumor

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~within 60 days of mri
This trial's timeline: 3 weeks for screening, Varies for treatment, and within 60 days of mri for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Repeatability coefficient
cerebral blood volume
the contrast agent extravasation rate constant (Ktrans, 1/min)
Secondary outcome measures
Intraclass correlation coefficient

Trial Design

2Treatment groups
Active Control
Group I: Validation of rCBV accuracyActive Control1 Intervention
64 subjects with primary glioma and 96 subjects with recurrent glioma. Subjects will be scanned using a single time-point to validate rCBV accuracy.
Group II: Development of advanced MRI methodsActive Control1 Intervention
Subjects with brain tumor. Subjects may be scanned using a single time-point to permit development and optimization of advanced MRI methods. Subjects may be scanned up to two times, with both visits occurring within one month, to permit analysis of test-retest reliability/repeatability.

Find a Location

Who is running the clinical trial?

St. Joseph's Hospital and Medical Center, PhoenixLead Sponsor
63 Previous Clinical Trials
14,485 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,654 Previous Clinical Trials
40,932,933 Total Patients Enrolled
C C Quarles, PhDPrincipal InvestigatorSt. Joseph's Hospital and Medical Center, Phoenix

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Development and Validation of Advanced MRI Methods for Clinical Applications
Lisa Arnold 2017. "Development and Validation of Advanced MRI Methods for Clinical Applications". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03264300.
~28 spots leftby Apr 2025
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