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Electroencephalography for Schizophrenia (NVEST Trial)

N/A

Waitlist Available

Led By Jonathan Wynn, PhD

Research Sponsored by VA Office of Research and Development

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 day

Awards & highlights

NVEST Trial Summary

This trial will examine the brain's ability to change its function or structure in response to changes in the environment or experiences in people with schizophrenia or TBI.

Eligible Conditions

Schizophrenia
Traumatic Brain Injury

NVEST Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 day

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 day

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 day for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Mismatch Negativity (MMN)

Visual Long-Term Potentiation (LTP) Task

Secondary outcome measures

Community Integration

Ekman Facial Affect Identification

Empathic Accuracy

+1 more

NVEST Trial Design

3Treatment groups

Experimental Treatment

Group I: People with TBIExperimental Treatment1 Intervention

People who have been diagnosed with a mild or moderate traumatic brain injury (TBI) and meet research criteria indicative of TBI within their lifetime.

Group II: People with SchizophreniaExperimental Treatment1 Intervention

People who have been diagnosed with schizophrenia and meet the investigators' research criteria for symptoms indicative of schizophrenia within their lifetime.

Group III: Healthy ControlsExperimental Treatment1 Intervention

People without a history of psychiatric illness or TBI and who do not meet research criteria for a psychiatric illness or TBI.

Do I qualify?Apply below to find out

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Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor

1,609 Previous Clinical Trials

3,306,531 Total Patients Enrolled

44 Trials studying Schizophrenia

5,092 Patients Enrolled for Schizophrenia

Jonathan Wynn, PhDPrincipal InvestigatorVA Greater Los Angeles Healthcare System, West Los Angeles, CA

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the current participant count in this experimental program?

"Affirmative. According to clinicaltrials.gov, this research endeavor has been open for recruitment since November 9th 2020 and was recently updated on the 2nd of November 2022. The team seeks 75 participants at a single medical centre."

Answered by AI

What aims is this research endeavor attempting to achieve?

"This trial lasting approximately 24 hours seeks to measure Mismatch Negativity (MMN) as its primary goal. Community Integration, Empathic Accuracy and Neurocognition are the secondary objectives; they will be measured through three distinct scales - the Lubben Social Network Scale, the Role Functioning Scale and the Community Integration Questionnaire – combined into one summary score with higher scores indicating better results. Additionally, participants must rate how people in video clips feel while recounting a personal story; this is correlated against ratings from those same individuals for an average correlation which determines empathic accuracy. Lastly, The MATRIC Consensus Cognitive Battery (MCC"

Answered by AI