← Back to Search

Aerobic Exercise Protocol for Post-Concussion Syndrome

N/A

Waitlist Available

Led By Chantel T Debert, MD MSc FRCPC

Research Sponsored by University of Calgary

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up repeated measure: pre-intervention, after 6-weeks of sp/aep, after 12-weeks of aep, 3-weeks post-aep, 9-weeks post-aep

Awards & highlights

Study Summary

This trial is investigating whether an aerobic exercise program can help adults with persistent post-concussive symptoms following a mild brain injury. 56 participants will be recruited from different programs in Calgary, Canada, and will either do a 6-week low-impact stretching protocol or a 12-week aerobic exercise protocol. They will then complete an online follow up 3 and 6 weeks post intervention.

Eligible Conditions

Post-Concussion Syndrome
Traumatic Brain Injury
Concussion

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ repeated measure: pre-intervention, after 6-weeks of sp/aep, after 12-weeks of aep, 3-weeks post-aep, 9-weeks post-aep

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~repeated measure: pre-intervention, after 6-weeks of sp/aep, after 12-weeks of aep, 3-weeks post-aep, 9-weeks post-aep

This trial's timeline: 3 weeks for screening, Varies for treatment, and repeated measure: pre-intervention, after 6-weeks of sp/aep, after 12-weeks of aep, 3-weeks post-aep, 9-weeks post-aep for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in symptom burden

Secondary outcome measures

Change in anxiety

Body Weight Changes

Change in cytokine profile

+7 more

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Aerobic Exercise Protocol (AEP)Experimental Treatment1 Intervention

Symptom threshold will be determined at baseline and repeated every 3 weeks using the Buffalo Concussion Treadmill Test. Briefly, there will be an initial 4min warm up at 1.7mph. The protocol will start with treadmill speed se to 3.3 mph and 0.0% incline. Each subsequent minute, the incline will increase by 1.0% to a max of 15%. At 15% grade, if the participant is still able to continue, treadmill speed will increase by 0.4mph each minute. Heart rate (HR) and rating of perceived excretion (RPE Borg scale) will be measured every minute. The test will be terminated upon symptom exacerbation at which time HR and RPE will be recorded. Every 3 weeks the symptom threshold test will be repeated for all participants and exercise prescription will be adjusted accordingly.

Group II: Stretching Protocol (SP)Placebo Group2 Interventions

The exercise testing for the stretching protocol to determine exercise prescription will be the same as described above.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Aerobic Exercise Protocol

2019

N/A

~60

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of CalgaryLead Sponsor

792 Previous Clinical Trials

869,102 Total Patients Enrolled

5 Trials studying Post-Concussion Syndrome

254 Patients Enrolled for Post-Concussion Syndrome

Hotchkiss Brain Institute, University of CalgaryOTHER

11 Previous Clinical Trials

2,380 Total Patients Enrolled

1 Trials studying Post-Concussion Syndrome

20 Patients Enrolled for Post-Concussion Syndrome

Chantel T Debert, MD MSc FRCPCPrincipal InvestigatorUniversity of Calgary

1 Previous Clinical Trials

10 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Would I be a suitable candidate for this investigation?

"To meet the qualifications of this clinical trial, patients must have been diagnosed with post-concussion syndrome and fall within an age range between 18 to 65 years old. At this time, 52 people are requested for recruitment."

Answered by AI

Does this research accommodate individuals in their later years?

"This medical trial is recruiting participants between the ages of 18 and 65. For those under 18 or over that age bracket, there are 175 trials available for minors and 713 studies dedicated to seniors respectively."

Answered by AI

Is recruitment for this trial currently ongoing?

"According to clinicaltrials.gov, the recruitment period for this trial has ended as of November 3rd 2022; however there are other 935 ongoing medical studies actively enrolling participants at present."

Answered by AI