This trial is evaluating whether Calcaneus Osteotomy (Bio-integrative) will improve 1 primary outcome and 2 secondary outcomes in patients with Bone Resorption. Measurement will happen over the course of 6 weeks.
This trial requires 44 total participants across 2 different treatment groups
This trial involves 2 different treatments. Calcaneus Osteotomy (Bio-integrative) is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"Symptoms of osteolysis that may be experienced include joint pain and stiffness, loss of bone mass, and possible joint deformity. Patients often undergo X-rays to rule out osteolytic lesions, and may be tested for low levels of calcium or vitamin D." - Anonymous Online Contributor
"In summary, this is the first study to describe spontaneous subperiosteal ossification in a human non-traumatic OA. The subperiosteal ossification appears not as a result of bone resorption or bone formation and is more likely the result of bone resorption which is a response to localized mechanical stress during physical activities." - Anonymous Online Contributor
"The cause of osteolysis is multifactorial. The primary mechanism is probably cytokine-mediated tissue destruction with further involvement of osteoclasts. The exact mechanism underlying this destructive process is still not totally known and further study is needed." - Anonymous Online Contributor
"The most common treatments for osteolysis include non-steroidal anti-inflammatory medications (e.g. aspirin, Ibuprofen), corticosteroids, orthopaedic surgery, and physical therapy. Most treatments involve an interdisciplinary approach." - Anonymous Online Contributor
"Achieving a definitive definition of osteolysis requires the application of stringent definitions; no studies of this nature have previously assessed this issue. Of the 11 studies that are included in the literature, none are based on data derived in clinical practice. However, one study was based on self-reported case definitions drawn from the literature. Results from a recent paper of this study indicate that osteolysis may be more widespread than previously thought and it is possible that the prevalence of this condition increases with age." - Anonymous Online Contributor
"Osteolysis can be cured. Patients can therefore feel confident that it will not recur if there is the usual, periodic follow-up. However, in order to prevent recurrence new symptoms must be noticed when bone remodelling has occurred." - Anonymous Online Contributor
"Based on these data it is hard to draw clear conclusions about this kind of procedure. Most of these articles were found by searching on web sites and some other searches like PubMed. However, according to a search the author found the most of the studies (about 21%) were published in “Western” countries. It is possible there could be a higher chance for b-ie-nj-o-t-o-s-is procedure to be considered for American patients, but it should be proven with more numbers of trials." - Anonymous Online Contributor
"The findings of this study suggest that calcaneus osteotomy is a safe procedure, providing the necessary time for restoration of bone mass before surgery. Additional randomized trials are warranted to definitively assess the efficacy of this surgical intervention for the management of non-traumatic femoral neck fractures." - Anonymous Online Contributor
"calcaneus osteotomy with integrative foot and ankle surgery is an effective method of improving foot function and relieving [metatarsalgia] as part of an overall treatment program." - Anonymous Online Contributor
"The use of a low-speed, oscillating air turbine was safer than conventional ultrasound, but the magnitude of osteolysis was similar. The use of conventional ultrasound did not result in improved mechanical properties compared to conventional ultrasonography. [NCT00918095]." - Anonymous Online Contributor
"As the sample size is small, further study is needed to identify if the combination of bone grafting and calcaneus osteotomy is better than just using osteotomy alone. The indications might also change with an increasing number of cases. Results from a recent clinical trial emphasizes the need for standardized studies to identify effective treatments for CMT." - Anonymous Online Contributor
"The application of bi-integrative (calcaneal osteotomy) calcaneal osteotomy is a valid treatment for the treatment of painful and severe osteoarthritic degeneration of the calcaneal spur in a diabetic patient with a high risk of amputation. This treatment is an adjunctive treatment approach, and has shown significant functional effect." - Anonymous Online Contributor