Whey Protein for Metabolic Bone Health

(BonePRO Trial)

Overseen By Silar Gardy, MSc

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: McGill University

Must not be taking: Hormonal contraceptives, Glucocorticoids, others

Disqualifiers: Thyroid disease, Eating disorder, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

14 Participants Needed

Trial Summary

What is the purpose of this trial?

The goal of this clinical trial is to investigate the effects of protein ingestion post-exercise on bone turnover markers. The main questions it aims to answer is: Does protein ingestion independently influence the bone metabolic response to exercise in endurance runners? We will compare dietary protein to a placebo (water) to detect changes in bone turnover markers. Participants will: In a within-subject design, participants will perform an exhaustive run and take either protein or placebo immediately post-exercise. Track physical activity and diet before each arm of the intervention and during the washout period.

Research Team

Jenna Gibbs, PhD

Principal Investigator

McGill University

Eligibility Criteria

This trial is for endurance runners who are interested in how protein affects their bone health after exercise. Participants should be healthy, with no metabolic bone diseases or conditions affecting metabolism. They must track their diet and activity, and not take other supplements that could influence the results.

Inclusion Criteria

Competitive runner for at least one season (minimum 40 km/week for the past 6-months)

I am between 18 and 35 years old.

My BMI is within the healthy range of 18.5 to 24.9.

Exclusion Criteria

My condition or medication affects my bone health.

I have been diagnosed with an eating disorder.

I do not have uncontrolled thyroid, digestive, or bone diseases.

Treatment Details

Interventions

• Whey Protein Supplement

Trial Overview The study tests if drinking whey protein right after running changes markers in the blood that show bone turnover compared to just drinking water. Runners will do an exhaustive run twice: once they'll have protein afterwards, and another time they'll have a placebo.

Participant Groups

Group I: Whey Protein Beverage Experimental Treatment 1 Intervention

Chocolate flavoured whey protein supplement as a post-exercise recovery beverage. One beverage post-exercise. Dose based on participant body weight.

Group II: Control Beverage Placebo Group 1 Intervention

Water beverage with calorie-free chocolate syrup as a post-exercise recovery beverage. Isovolumetric.

Who Is Running the Clinical Trial?

McGill University

Lead Sponsor

Trials

421

Recruited

1,017,000+