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Stem Cell Therapy

Bone Marrow Concentrate for Discogenic Pain

N/A
Waitlist Available
Led By David S Levi, MD
Research Sponsored by APM Spine and Sports Physicians
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3, 6, 12 months
Awards & highlights

Study Summary

This trial is testing whether injecting bone marrow concentrate into the discs of people with discogenic low back pain can help relieve their pain. The study is double-blind, meaning that neither the participants nor the researchers will know who is receiving the treatment until after the study is over.

Eligible Conditions
  • Discogenic Pain

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3, 6, 12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3, 6, 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Functional improvement vs Placebo group 50%
Secondary outcome measures
Functional improvement treatment vs placebo 30%
Functional improvement treatment vs placebo 50%
Pain
+1 more
Other outcome measures
Adjunct therapy
Medication usage

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Bone Marrow ConcentrateExperimental Treatment1 Intervention
Patients in this group will receive injection of autologous bone marrow concentrate into the suspected painful intervertebral discs.
Group II: Placebo GroupPlacebo Group1 Intervention
Patients in this group will receive an injection of normal saline dorsal to the transverse process. The bone marrow aspiration will be simulated for these patients.

Find a Location

Who is running the clinical trial?

APM Spine and Sports PhysiciansLead Sponsor
David S Levi, MDPrincipal InvestigatorJordan Young Institute
Scott I Horn, DOStudy ChairJordan Young Institute

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
PM&RJournal
Applications of Platelet-rich Plasma in Musculoskeletal and Sports Medicine: An Evidence-based Approach
Nguyen, Rosalyn T., Joanne Borg-Stein, and Kelly McInnis. 2011. “Applications of Platelet-rich Plasma in Musculoskeletal and Sports Medicine: An Evidence-based Approach”. Pm&r. Wiley. doi:10.1016/j.pmrj.2010.11.007.
BioMed Research InternationalJournal
Efficacy of Autologous Bone Marrow Concentrate for Knee Osteoarthritis with and Without Adipose Graft
Centeno, Christopher, John Pitts, Hasan Al-Sayegh, and Michael Freeman. 2014. “Efficacy of Autologous Bone Marrow Concentrate for Knee Osteoarthritis with and Without Adipose Graft”. Biomed Research International. Hindawi Limited. doi:10.1155/2014/370621.
The American Journal of Sports MedicineJournal
A Prospective, Single-blind, Placebo-controlled Trial of Bone Marrow Aspirate Concentrate for Knee Osteoarthritis
Shapiro, Shane A., Shari E. Kazmerchak, Michael G. Heckman, Abba C. Zubair, and Mary I. O’Connor. 2016. “A Prospective, Single-blind, Placebo-controlled Trial of Bone Marrow Aspirate Concentrate for Knee Osteoarthritis”. The American Journal of Sports Medicine. SAGE Publications. doi:10.1177/0363546516662455.
Journal of Pain ResearchJournal
A Prospective Multi-site Registry Study of a Specific Protocol of Autologous Bone Marrow Concentrate for the Treatment of Shoulder Rotator Cuff Tears and Osteoarthritis
Bashir, Jamil, Christopher Centeno, Michael Freeman, Hasan Al-Sayegh, and Shaun Goodyear. 2015. “A Prospective Multi-site Registry Study of a Specific Protocol of Autologous Bone Marrow Concentrate for the Treatment of Shoulder Rotator Cuff Tears and Osteoarthritis”. Journal of Pain Research. Informa UK Limited. doi:10.2147/jpr.s80872.
All > Low Back Pain > Back Pain
~9 spots leftby Apr 2025
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