← Back to Search

EASE for Autism Spectrum Disorder (EASE Trial)

N/A

Waitlist Available

Led By Susan White

Research Sponsored by University of Pittsburgh

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up the cgi-i will be completed at 16 weeks (post-treatment)

Awards & highlights

EASE Trial Summary

This trial will test a new intervention to improve emotion regulation in adolescents with ASD. If successful, this could lead to reduced maladaptive behavior and improved quality of life for those with ASD and their families.

Eligible Conditions

Autism Spectrum Disorder
Autism

EASE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ the edi-sf will be completed at 16 weeks (post-treatment).

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~the edi-sf will be completed at 16 weeks (post-treatment).

This trial's timeline: 3 weeks for screening, Varies for treatment, and the edi-sf will be completed at 16 weeks (post-treatment). for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

The Clinical Global Impression Scale- Improvement (CGI-I)

Secondary outcome measures

Brief Psychiatric Rating Scale (BPRS)

Emotion Dysregulation Inventory Reactivity Scale Short Form (EDI-SF)

EASE Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Emotion Awareness/Skills EnhancementExperimental Treatment1 Intervention

EASE Therapy includes 16 weekly sessions focused on mindfulness exercise, review of prior content, practicing prior skills, outline of current session, discussion of the new skill, handouts, practice and plan for out of session practice held in Webster Hall in Pittsburgh, at the Center for the Prevention of Youth Behavior Problems in Tuscaloosa or via telehealth conferencing software. The investigators will apply a multimodal teaching approach, where individual therapy is buttressed by parent involvement and practice sessions in the youth's community. A secure website developed for this project (emotion-Coach or "e-Coach") will augment the intervention by providing online supports to increase treatment intensity or dosage. There will be specific information on how to reinforce the skills at home and in the community.

Group II: Supportive TherapyActive Control1 Intervention

Supportive Therapy will involve attending 16 weekly therapy sessions held in Webster Hall in Pittsburgh, at the Center for the Prevention of Youth Behavior Problems in Tuscaloosa or via telehealth conferencing software. The intervention will not involve mindfulness or other emotion regulation strategies used in EASE. The therapy will be tailored to the individual's needs and will include aspects common in supportive therapy such as reflective listening, antecedent management, and problem-solving. This program does not have an online component.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

EASE

2015

N/A

~160

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor

1,719 Previous Clinical Trials

16,342,228 Total Patients Enrolled

15 Trials studying Autism Spectrum Disorder

10,341 Patients Enrolled for Autism Spectrum Disorder

University of Alabama at BirminghamOTHER

1,581 Previous Clinical Trials

2,277,916 Total Patients Enrolled

6 Trials studying Autism Spectrum Disorder

914 Patients Enrolled for Autism Spectrum Disorder

Susan WhitePrincipal InvestigatorUniversity of Alabama at Birmingham

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still vacancies for this research endeavor?

"Clinicaltrials.gov indicates that this clinical trial is no longer actively recruiting patients, as it was initially posted on the 30th of January 2018 and last updated on the 6th of September 2022. However, there are currently 253 other trials looking for participants now."

Answered by AI

Is there an age restriction for individuals considered to join the trial?

"This medical trial's requirements state that the age range to be admitted is between 12 and 21 years old. There are 213 clinical trials for minors and 41 studies open to elderly patients over 65."

Answered by AI

What eligibility criteria must be met to join this scientific experiment?

"This medical trial requires 100 individuals with an Autism Spectrum Disorder (ASD) diagnosis, ranging in age from 12 to 21 years old. Additionally, applicants must meet the following criteria: Diagnosis of ASD based on ADOS-2 or ADI-R cutoffs; Average verbal intellectual ability according to WASI-2 FSIQ score of 75 or higher; Parent/guardian attendance at sessions and assessments; Emotional regulation problems reported by parent/caretaker. If previous testing via ADOS has been completed within 3 years prior and a consent form is signed for data release, another test will not be required."

Answered by AI