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Massage for Muscle Wasting

N/A

Waitlist Available

Led By Esther Dupont-Versteegden, Ph.D.

Research Sponsored by Esther Dupont-Versteegden

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 9 days

Awards & highlights

Study Summary

This trial will test if massage can help reduce muscle loss after a period of inactivity.

Eligible Conditions

Muscle Wasting

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 9 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~9 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and 9 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Percent change in myofiber Cross Sectional Area (CSA).

Percent change in myofibrillar protein synthesis (MyoKsyn).

Secondary outcome measures

Extracellular Fluid

Percent change in the expression of muscle Rab27b mRNA.

Trial Design

4Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: Immobilization MassageExperimental Treatment1 Intervention

Following baseline assessments, participants will be randomized into the unilateral lower limb suspension group undergoing atrophy for the remainder of the study. Four massage treatments will be applied every other day until the end of the study.

Group II: Ambulatory ControlActive Control1 Intervention

Following baseline assessments, participants will be randomized into the ambulatory group for the remainder of the study. Atrophy will not be induced and massage intervention will not be applied. Ambulatory groups will be recruited following the immobilized groups.

Group III: Immobilization ControlActive Control1 Intervention

Following baseline assessments, participants will be randomized into the unilateral lower limb suspension group undergoing atrophy for the remainder of the study. Massage intervention will not be applied.

Group IV: Ambulatory MassagePlacebo Group1 Intervention

Following baseline assessments, participants will be randomized into the ambulatory group for the remainder of the study. No atrophy induction. Four massage treatments will be applied every other day until the end of the study. Ambulatory groups will be recruited following the immobilized groups.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of OklahomaOTHER

455 Previous Clinical Trials

97,577 Total Patients Enrolled

Esther Dupont-VersteegdenLead Sponsor

National Center for Complementary and Integrative Health (NCCIH)NIH

832 Previous Clinical Trials

668,897 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research protocol accept participants aged 45 and above?

"To be eligible to join this trial, individuals must range between 18-30 years old. Correspondingly, there are 47 trials dedicated to minors and 151 for seniors."

Answered by AI

Is this trial currently seeking participants to join?

"All evidence points to this clinical trial still being open for recruitment, as it was initially posted on August 1st 2020 and last adjusted on October 5th 2022."

Answered by AI

Is it possible for me to become a participant in this research endeavor?

"This study is recruiting 140 individuals with muscular dystrophy, aged 18 to 30. All genders and racial backgrounds are welcome to apply; however all participants must be non-smokers in good health."

Answered by AI

How many individuals are involved in this research endeavor?

"Confirmed. The clinicaltrials.gov website indicates that this trial has been ongoing since August 1st, 2020 and is currently searching for 140 participants from one medical facility. It was last updated on October 5th 2022"

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Mechanisms Underlying Local and Systemic Effects of Massage

Esther Dupont-Versteegden 2020. "Mechanisms Underlying Local and Systemic Effects of Massage". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04131712.