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Ablation for Atrial Fibrillation (COAST-AF RCT Trial)
COAST-AF RCT Trial Summary
This trial is testing whether adding atrial scar mapping to pulmonary vein isolation (PVI) is more effective than PVI alone in treating patients with persistent atrial fibrillation (AF).
COAST-AF RCT Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowCOAST-AF RCT Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.COAST-AF RCT Trial Design
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Who is running the clinical trial?
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- You have had a procedure called catheter ablation for atrial fibrillation or left atrial flutter in the past.You have had surgery to treat atrial fibrillation in the past.You have a blood clot inside your heart.Treatable reasons for atrial fibrillation.You cannot take medication to prevent blood clots.You have ongoing symptoms from atrial fibrillation and need a catheter ablation procedure for it.You have had a specific type of irregular heartbeat that lasted for more than 3 months, which was confirmed by different heart monitoring tests within the past 36 months.Your DR-FLASH score is 4 or higher.You have a heart condition called hypertrophic cardiomyopathy.You have a serious problem with one of your heart valves.You have another health condition that is expected to significantly shorten your life.
- Group 1: Pulmonary Vein Isolation and scar ablation
- Group 2: Pulmonary Vein Isolation
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is enrollment open for this research project yet?
"Affirmative, the details accessible via clinicaltrials.gov point to this medical trial being actively recruiting patients. It was established on August 24th of 2018 and has since been amended November 2nd 2021. A total of 502 participants are required for the 15 sites involved in the study."
How many healthcare facilities are currently conducting this trial?
"This research endeavour is presently running in 15 different locations, including Sherbrooke, Toronto and Quebec City. To facilitate the process of enrollment it is best to select a clinic close to you so as to reduce any travelling needs."
What is the upper limit of participants for this research endeavor?
"Correct. Clinicaltrials.gov data verifies that this trial, initially posted on August 24th 2018, is actively enrolling participants. 502 patients must be enrolled from 15 separate medical centres."
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