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Asthmatics for Exercise-Induced Asthma

N/A
Waitlist Available
Led By David A. Kaminsky, MD
Research Sponsored by University of Vermont
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up before and after hyperpnea challenge
Awards & highlights

Study Summary

This research is being conducted to help us better understand what causes exercise induced asthma. The investigators hypothesize that two types of chemicals, cysteinyl leukotrienes and adenosine, play an important role. The investigators will be measuring these chemicals in the exhaled breath of volunteers with exercise induced asthma as they undergo a test to mimic exercise induced asthma. The investigators will determine how the levels of these chemicals change in association with how lung function changes before, during and after an episode of exercise induced asthma.

Eligible Conditions
  • Exercise-Induced Asthma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~before and after hyperpnea challenge
This trial's timeline: 3 weeks for screening, Varies for treatment, and before and after hyperpnea challenge for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in level of cystLTs and adenosine
Secondary outcome measures
Change in pH of EBC and change in pulmonary function

Trial Design

1Treatment groups
Experimental Treatment
Group I: AsthmaticsExperimental Treatment1 Intervention
Asthmatics with exercise induced bronchospasm
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Hyperpnea challenge
2007
N/A
~10

Find a Location

Who is running the clinical trial?

University of VermontLead Sponsor
268 Previous Clinical Trials
3,743,737 Total Patients Enrolled
David A. Kaminsky, MDPrincipal InvestigatorUniversity of Vermont

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Role of Leukotrienes and Adenosine in Hyperpnea-induced Bronchospasm
David Kaminsky, MD 2007. "Role of Leukotrienes and Adenosine in Hyperpnea-induced Bronchospasm". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00710255.
~0 spots leftby May 2025
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