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Procedure

ISAFE technique for Conduction Anesthesia (ISAFE Trial)

N/A

Waitlist Available

Research Sponsored by University of Toronto

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 24 and 48 hours

Awards & highlights

ISAFE Trial Summary

This trial is testing a new way to do a continuous adductor canal block, which is a type of surgery that numbs your leg. They think it might be better than the old way, because it might result in fewer problems with the catheter (the thing that numbs your leg) coming out.

Eligible Conditions

Conduction Anesthesia
Knee Replacement Surgery

ISAFE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 24 and 48 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~24 and 48 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 and 48 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Catheter dislodgement

Secondary outcome measures

Incidence of catheter insertion related complications

Incidence of sensory block

Number of attempts for catheter insertion

+4 more

ISAFE Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: ISAFE techniqueExperimental Treatment1 Intervention

Adductor canal block catheter tip located in the fascial plane between sartorious muscle and femoral artery.

Group II: Conventional techniqueActive Control1 Intervention

Adductor canal block catheter tip located in lateral to the femoral artery.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of TorontoLead Sponsor

689 Previous Clinical Trials

1,018,543 Total Patients Enrolled

Mount Sinai Hospital, CanadaOTHER

196 Previous Clinical Trials

67,508 Total Patients Enrolled

Yehoshua Gleicher, MD, MScStudy ChairUniversity of Toronto

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this investigation still recruiting individuals to participate?

"Affirmative. According to clinicaltrials.gov, this clinical trial is currently recruiting participants after being initially launched on March 25th 2022 and last updated April 13th 2022. 100 test subjects have been requested from one medical centre."

Answered by AI

What is the capacity of the participants in this medical study?

"Affirmatively, the clinical trial's most recent information on clinicaltrials.gov indicates that it is currently seeking participants. This medical study was initially posted on March 25th 2022 and last modified April 13th 2022 with a goal of enrolling 100 patients from one location."

Answered by AI

Recent research and studies

Journal of Clinical AnesthesiaJournal

Postoperative Continuous Adductor Canal Block for Total Knee Arthroplasty Improves Pain and Functional Recovery: A Randomized Controlled Clinical Trial

Leung, Patrick, David M. Dickerson, Sahitya K. Denduluri, Maryam K. Mohammed, Min Lu, Magdalena Anitescu, and Hue H. Luu. 2018. “Postoperative Continuous Adductor Canal Block for Total Knee Arthroplasty Improves Pain and Functional Recovery: A Randomized Controlled Clinical Trial”. Journal of Clinical Anesthesia. Elsevier BV. doi:10.1016/j.jclinane.2018.06.004.

The LancetJournal

Knee Replacement

Price, Andrew J, Abtin Alvand, Anders Troelsen, Jeffrey N Katz, Gary Hooper, Alastair Gray, Andrew Carr, and David Beard. 2018. “Knee Replacement”. The Lancet. Elsevier BV. doi:10.1016/s0140-6736(18)32344-4.

Current Pain and Headache ReportsJournal

Anesthetic and Analgesic Management for Outpatient Knee Arthroplasty

Cullom, Chris, and Jonathan T. Weed. 2017. “Anesthetic and Analgesic Management for Outpatient Knee Arthroplasty”. Current Pain and Headache Reports. Springer Science and Business Media LLC. doi:10.1007/s11916-017-0623-y.

MedicineJournal