1238 Participants Needed

Registry for Juvenile Arthritis

Recruiting at 16 trial locations
JG
FM
MS
Overseen ByMartha Sieres
Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: University of British Columbia
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to collect and analyze data from children in Canada newly diagnosed with Juvenile Idiopathic Arthritis (JIA), a condition causing long-term joint inflammation. Researchers seek to understand disease progression and gather information to improve future treatments and healthcare decisions. Children diagnosed with JIA in the last three months and those who participated in certain past studies might be suitable for this trial. Participants will provide valuable insights that could lead to better management of JIA and potentially improved outcomes for affected children.

As an unphased trial, this study offers a unique opportunity for participants to contribute to foundational research that could shape future JIA treatments and healthcare strategies.

Why are researchers excited about this trial?

The CAPRI National Juvenile Idiopathic Arthritis Registry is unique because it aims to gather comprehensive data on patients with juvenile idiopathic arthritis (JIA) across various treatment regimens. Unlike standard care options like NSAIDs, methotrexate, or biologics, which focus on symptom management, this registry seeks to identify patterns and outcomes that could lead to more personalized and effective treatment strategies. Researchers are excited about this trial because it has the potential to improve our understanding of which therapies work best for different subtypes of JIA, ultimately leading to better, more tailored treatment options for young patients.

Who Is on the Research Team?

JG

Jaime Guzman, MD, FRCPC

Principal Investigator

University of British Columbia

AH

Adam Huber, MD

Principal Investigator

IIWK Health Centre, Halifax, Nova Scotia, Canada

CD

Ciaran Duffy, MD

Principal Investigator

Children's Hospital of Eastern Ontario, Ottawa, Ontario

GC

Gaëlle Chédeville, MD

Principal Investigator

McGill University Health Centre/Research Institute of the McGill University Health Centre

HS

Heinrike Schmeling, MD

Principal Investigator

University of Calgary / Alberta Children's Hospital

LH

Linda Hiraki, MD,FRCPC,MS

Principal Investigator

Hospital for Sick Children (SickKids)

SB

Susanne Benseler, MD, PhD

Principal Investigator

University of Calgary / Alberta Children's Hospital

MT

Marinka Twilt, MD MSCE PhD

Principal Investigator

University of Calgary / Alberta Children's Hospital

Are You a Good Fit for This Trial?

Inclusion Criteria

All patients newly diagnosed with JIA within the last 3 months
All patients who participated in the original ReACCh-Out study
LEAP study patients from 'newly diagnosed' and 'ReACCh-Out' cohorts who have completed their two year follow up in LEAP

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Registry Enrollment

Participants are enrolled in the CAPRI JIA registry, with initial data collection and consent process

1 visit
1 visit (in-person)

Data Collection

Ongoing data collection from clinic visits, including annual updates and monitoring of disease course and outcomes

Ongoing

Follow-up

Participants are monitored for disease activity, functional disability, pain intensity, and quality of life over one year

1 year

What Are the Treatments Tested in This Trial?

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of British Columbia

Lead Sponsor

Trials
1,506
Recruited
2,528,000+

IWK Health Centre

Collaborator

Trials
131
Recruited
112,000+

Alberta Children's Hospital

Collaborator

Trials
58
Recruited
44,700+

Children's Hospital of Eastern Ontario

Collaborator

Trials
134
Recruited
61,000+

The Hospital for Sick Children

Collaborator

Trials
724
Recruited
6,969,000+

London Health Sciences Centre

Collaborator

Trials
151
Recruited
60,400+

Royal University Hospital Foundation

Collaborator

Trials
23
Recruited
7,900+

University of Manitoba

Collaborator

Trials
628
Recruited
209,000+

McMaster Children's Hospital

Collaborator

Trials
43
Recruited
19,900+

University of Calgary

Collaborator

Trials
827
Recruited
902,000+
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