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Stimulant

Energy Drink Ingredients and Exercise for Arrhythmia (EEDICF Trial)

N/A

Waitlist Available

Research Sponsored by Duquesne University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 0, 1, 2, 4, hours post-dose

Awards & highlights

EEDICF Trial Summary

This trial will test the hypothesis that the ingredients in energy drinks interact to cause increased systolic blood pressure and heart rate. The study will also test whether energy drinks cause changes in electrical activity of the heart that can be measured by an ECG. The study will enroll 300 participants who will be randomly assigned to one of four study groups. The first group will consume two cans of an energy drink per day for 3 days. The second group will consume two cans of an energy drink per day for 3 days along with a daily supplement of taurine. The third group will consume two cans of an energy drink per day for 3 days along with a

Eligible Conditions

Arrhythmia
High Blood Pressure

EEDICF Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 0, 1, 2, 4, hours post-dose

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~0, 1, 2, 4, hours post-dose

This trial's timeline: 3 weeks for screening, Varies for treatment, and 0, 1, 2, 4, hours post-dose for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in QTc interval of EKG

Secondary outcome measures

Change in Heart Rate

Change in Systolic and Diastolic Blood Pressure

EEDICF Trial Design

4Treatment groups

Experimental Treatment

Group I: Changes in BP, HR and EKG with Test Solution C and ExerciseExperimental Treatment1 Intervention

Subject baseline HR, BP, ECG recorded. Subject will ingest sucrose (150g); caffeine (400 mg); taurine (4,000 mg); carnitine (400 mg) 30 min later, subject will exercise on a treadmill

Group II: Changes in BP, HR and EKG with Test Solution CExperimental Treatment1 Intervention

Subject baseline HR, BP, ECG recorded. Subject will ingest sucrose (150g); caffeine (400 mg); taurine (4,000 mg); carnitine (400 mg)

Group III: Changes in BP, HR and EKG with Test Solution B and ExerciseExperimental Treatment1 Intervention

Subject baseline HR, BP, ECG recorded. Subject will ingest sucrose (150g); caffeine (400 mg) 30 min later, subject will exercise on a treadmill Subjects will return each week to repeat the above procedures with a different test solution.

Group IV: Changes in BP, HR and EKG with Test Solution A and ExerciseExperimental Treatment1 Intervention

Subject baseline HR, BP, EKG recorded. Subject will ingest sucrose (150g): 30 min later, subject will exercise on a treadmill Subjects will return each week to repeat the above procedures with a different test solution.

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Who is running the clinical trial?

Duquesne UniversityLead Sponsor

30 Previous Clinical Trials

2,393 Total Patients Enrolled

David Delmonico, Ph.D.Study ChairInstitutional Review Board, Chair, Duquesne University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the enrollment for this experiment restricted to elders aged 85 and younger?

"The age range of participants accepted into this medical trial is between 18 to 39 years old."

Answered by AI

What criteria must an individual meet to qualify for this study?

"The requirements for enrollment in this clinical trial are as follows: a blood pressure reading within acceptable limits and an age between 18-39. There are 35 spots available to fill."

Answered by AI

How many individuals have enrolled in the experiment so far?

"Indeed, the clinicaltrials.gov database exhibits that this trial is presently in search of participants. It was initially advertised on January 1st 2020 and recently revised March 19th 2021. The study necessitates 35 individuals to be recruited from a single medical centre."

Answered by AI

Are researchers recruiting participants to join this medical experiment?

"Affirmative. Clinicaltrials.gov states that this trial, which first appeared on January 1st 2020, is currently recruiting participants. This medical investigation needs 35 patients from a single location to complete the study."

Answered by AI

Recent research and studies

Regulatory Toxicology and PharmacologyJournal

Caffeine and Cardiovascular Health

Turnbull, Duncan, Joseph V. Rodricks, Gregory F. Mariano, and Farah Chowdhury. 2017. “Caffeine and Cardiovascular Health”. Regulatory Toxicology and Pharmacology. Elsevier BV. doi:10.1016/j.yrtph.2017.07.025.

Biochimica et Biophysica Acta (BBA) - Molecular Cell ResearchJournal

Carnitine Transport and Fatty Acid Oxidation

Longo, Nicola, Marta Frigeni, and Marzia Pasquali. 2016. “Carnitine Transport and Fatty Acid Oxidation”. Biochimica Et Biophysica Acta (BBA) - Molecular Cell Research. Elsevier BV. doi:10.1016/j.bbamcr.2016.01.023.

Advances in Experimental Medicine and BiologyJournal

Cardiac Actions of Taurine as a Modulator of the Ion Channels

Satoh, Hiroyasu. 1998. “Cardiac Actions of Taurine as a Modulator of the Ion Channels”. Advances in Experimental Medicine and Biology. Springer US. doi:10.1007/978-1-4899-0117-0_16.

The American Journal of Emergency MedicineJournal