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Local for Appendicitis

N/A
Waitlist Available
Research Sponsored by Valley Anesthesiology Consultants
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients undergoing Appendectomy for acute non-perforated appendicitis Must be between 9-17 years old
Be younger than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 hours
Awards & highlights

Study Summary

Patient will have usual appendectomy surgery with an injection of local or saline at incision site either before or after the incision at random. The clinical hypothesis of this trial is that pediatric patients who undergo a local anesthetic pre-incisional and/or post-incisional will reduce the amount of postoperative pain and therefore reduce the amount of analgesics required to keep the patient satisfied. Primary: To determine if local anesthetic reduces postoperative pain. Secondary: To assess the timing of local anesthetic injection affects postoperative pain.

Eligible Conditions
  • Appendicitis
  • Postoperative Pain

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Amount of Post Operative Pain Patients Experience
Secondary outcome measures
The total amount of opioid use

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: LocalExperimental Treatment2 Interventions
Patient will be given a total of 0.5 mL/kg of 0.25% Bupivicaine either pre-incision: local will be to be given intradermally and onto the peritoneum under direct vision; or post-closure local will be injected intradermally after closure
Group II: SalinePlacebo Group2 Interventions
Patient will be given saline with a maximum of 30 cc either pre-incision: local will be to be given intradermally and onto the peritoneum under direct vision; or post-closure local will be injected intradermally after closure

Find a Location

Who is running the clinical trial?

Valley Anesthesiology ConsultantsLead Sponsor
3 Previous Clinical Trials
103 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Pediatric AnesthesiaJournal
A Retrospective Study of Multimodal Analgesic Treatment After Laparoscopic Appendectomy in Children
Liu, Yang, Catherine Seipel, Monica E. Lopez, Jed G. Nuchtern, Mary L. Brandt, Sara C. Fallon, Peter A. Manyang, Imelda M. Tjia, Rahul G. Baijal, and Mehernoor F. Watcha. 2013. “A Retrospective Study of Multimodal Analgesic Treatment After Laparoscopic Appendectomy in Children”. Edited by Per-Arne Lonnqvist. Pediatric Anesthesia. Wiley. doi:10.1111/pan.12271.
Pediatric AnesthesiaJournal
Substantial Postoperative Pain Is Common Among Children Undergoing Laparoscopic Appendectomy
Tomecka, Maggie J., Andrey V. Bortsov, Natalie R. Miller, Natalie Solano, John Narron, Peggy P. McNaull, Karene J. Ricketts, Concetta M. Lupa, and Samuel A. McLean. 2011. “Substantial Postoperative Pain Is Common Among Children Undergoing Laparoscopic Appendectomy”. Pediatric Anesthesia. Wiley. doi:10.1111/j.1460-9592.2011.03711.x.
clinicaltrials.govStudy
Evaluation of Local Anesthetic at Incision Site
Neil Raj Singhal 2015. "Evaluation of Local Anesthetic at Incision Site". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02483689.
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~10 spots leftby Apr 2025
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