← Back to Search

N/A

ERGO for Sleep Apnea (OBEX1 Trial)

N/A
Waitlist Available
Led By Jean-Louis Pepin, MD, PhD
Research Sponsored by AGIR à Dom
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
OSAS (AHI > 30 before CPAP treatment)
> 4h/d CPAP treatment adherence
Timeline
Screening 3 weeks
Treatment Varies
Follow Up every year from the 1st to the 5th year
Awards & highlights

OBEX1 Trial Summary

The study was designed to test the following hypotheses: In obese patients with OSAS, the benefit of the combination of exercise training + continuous positive airway pressure (CPAP) will be higher than CPAP alone in term of functional capacity, metabolic, inflammatory, cardiovascular and sleep parameters and quality of life. In obese patients with OSAS, the benefit of training using ventilatory assistance (NIV) during cycloergometer [cycloergometer with NIV] or respiratory muscles training (spirotiger) in addition to cycloergometer [cycloergometer + spirotiger] will be higher than cycloergometer training alone [cycloergometer] in term of functional and exercise capacities. Dyspnea during walking test and respiratory muscle strength at baseline could influence the response to combined exercise training such as [cycloergometer + NIV] or [cycloergometer + spirotiger]

Eligible Conditions
  • Sleep Apnea
  • Obesity

OBEX1 Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

OBEX1 Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~every year from the 1st to the 5th year
This trial's timeline: 3 weeks for screening, Varies for treatment, and every year from the 1st to the 5th year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Baseline characteristics
Change in exercise tolerance during walking test
Change in physical activity and sleep duration
+6 more

OBEX1 Trial Design

2Treatment groups
Active Control
Group I: ERGOActive Control1 Intervention
General endurance training on cycloergometer
Group II: ERGONIV/ ERGOSPIROActive Control1 Intervention
General endurance training on cycloergometer using ventilatory assistance (ERGONIV) or additional respiratory muscle training (ERGOSPIRO)

Find a Location

Who is running the clinical trial?

University Hospital, GrenobleOTHER
793 Previous Clinical Trials
249,817 Total Patients Enrolled
12 Trials studying Sleep Apnea
2,733 Patients Enrolled for Sleep Apnea
AGIR à DomLead Sponsor
34 Previous Clinical Trials
5,040 Total Patients Enrolled
4 Trials studying Sleep Apnea
285 Patients Enrolled for Sleep Apnea
Jean-Louis Pepin, MD, PhDPrincipal InvestigatorLaboratoire EFCR, CHU de Grenoble, 38043, Grenoble, France
1 Previous Clinical Trials
15 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
OBese Patients With Obstructive Sleep Apnea Syndrome(OSAS) and EXercise Training
2010. "OBese Patients With Obstructive Sleep Apnea Syndrome(OSAS) and EXercise Training". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01155271.
All > Apnea > Sleep
~4 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top