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Communication Bridge™ for Primary Progressive Aphasia

N/A

Waitlist Available

Led By Emily Rogalski, Ph.D.

Research Sponsored by Northwestern University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 5 assessment time points through study completion, an average of 1 year, including change over time

Awards & highlights

Study Summary

This trial will compare two types of speech language therapy to see which is more effective in treating mild Primary Progressive Aphasia. The study will last for 12 months and involve 5 evaluations and 15 therapy sessions, as well as access to a personalized web application. There is no cost to participate.

Eligible Conditions

Primary Progressive Aphasia

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 5 assessment time points through study completion, an average of 1 year, including change over time

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~5 assessment time points through study completion, an average of 1 year, including change over time

This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 assessment time points through study completion, an average of 1 year, including change over time for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Communication Confidence PROM

Change in Communication Participation PROM

Change in Communication Participation Person Centered Goals

Other outcome measures

Change in Script accuracy (trained scripts)

Change in Word accuracy (trained words)

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Communication Bridge™Experimental Treatment1 Intervention

Participants receive Communication Bridge™, a multi-component, participation-focused, dyadic intervention in which both the person with PPA and their co-enrolled communication partner are intervention recipients. Communication Bridge™ is modelled on the Living with Aphasia: Framework for Outcome Measurement (A-FROM) and the Care Pathway Model that was developed for persons living with primary progressive aphasia. Consistent with participation-focused intervention models personally salient training stimuli are incorporated into all therapy activities in the Experimental arm.

Group II: Evidence-Based Impairment FocusedActive Control1 Intervention

The Control arm includes a non-dyadic intervention in which the person with PPA is the active intervention recipient and their communication partner is in a supporting role. In the Control arm, participants receive a speech-language intervention designed to address impairment and functional limitations, comprised of activities that address word retrieval and 'automatic' speech production using fixed, non-personalized, stimuli across participants.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Communication Bridge™

2018

N/A

~110

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Who is running the clinical trial?

Northwestern UniversityLead Sponsor

1,584 Previous Clinical Trials

917,670 Total Patients Enrolled

National Institute on Aging (NIA)NIH

1,666 Previous Clinical Trials

28,005,034 Total Patients Enrolled

Emily Rogalski, Ph.D.Principal Investigator - Northwestern University

Northwestern University

1 Previous Clinical Trials

70 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What requirements must a participant meet to join this investigation?

"This clinical trial has a requirement for 95 participants aged between 30 and 100 who have primary progressive aphasia(ppa). Candidates must also verify that they are 18 years or older, can read printed material with either aided of unaided vision, comprehend conversation in crowded rooms through hearing alone or assisted devices, score no more than 9 on Geriatric Depression Scale tests and show aptitude with technology to successfully use video conferencing and the Communication Bridge™ web application."

Answered by AI

Have registrations for this experiment ceased or are they ongoing?

"According to clinicaltrials.gov, this particular study has ceased its recruitment efforts since the last edit on November 8th 2022. However, there are 119 other medical trials actively recruiting candidates at present."

Answered by AI