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Comprehension Acquired Brain Injury for Aphasia

N/A
Waitlist Available
Led By Kelly K Knollman-Porter, PhD
Research Sponsored by Miami University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measured 1 week and 4 weeks post termination of treatment
Awards & highlights

Study Summary

The purpose of this two phase study is to evaluate comprehension by people with acquired brain injury. The phase 1 portion of the study will examine comprehension of narrative paragraphs under 3 conditions: (a) written text only, (b) auditory output only (i.e., synthetic speech - David voice) or combined written text and auditory output. The phase 2 portion of the study is to evaluate comprehension of sentences and paragraphs produced with computer generated (synthesized) speech and digitized natural speech after multiple exposures.

Eligible Conditions
  • Aphasia
  • Traumatic Brain Injury

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~measured 1 week and 4 weeks post termination of treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and measured 1 week and 4 weeks post termination of treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Comprehension Across Conditions (Study 1 of 2)
Repeated Exposure to Digitized and Synthetic Speech (Study 2 of 2)
Secondary outcome measures
Comprehension Generalization
Perceived Comprehension Accuracy

Trial Design

1Treatment groups
Experimental Treatment
Group I: Comprehension Acquired Brain InjuryExperimental Treatment1 Intervention
All participants will be exposed to 3 conditions: (a) written text, (b) auditory output (synthetic speech), and combined conditions for study 1. For study 2 participants will be repeatedly exposed to synthetic speech output to determine the influence on comprehension. Participants are not required to participate in both studies.

Find a Location

Who is running the clinical trial?

Duquesne UniversityOTHER
30 Previous Clinical Trials
2,368 Total Patients Enrolled
2 Trials studying Aphasia
159 Patients Enrolled for Aphasia
University of ArizonaOTHER
514 Previous Clinical Trials
148,534 Total Patients Enrolled
3 Trials studying Aphasia
202 Patients Enrolled for Aphasia
Miami UniversityLead Sponsor
13 Previous Clinical Trials
2,606 Total Patients Enrolled
1 Trials studying Aphasia
152 Patients Enrolled for Aphasia

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Narrative Comprehension by People With Acquired Brain Injury
Kelly Knollman-Porter 2017. "Narrative Comprehension by People With Acquired Brain Injury". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03309930.
All > Brain Injury
~8 spots leftby Apr 2025
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