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Therapy for Aphasia

N/A

Waitlist Available

Led By Chaleece W Sandberg, Ph.D.

Research Sponsored by Penn State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at baseline and at approximately 10 weeks (i.e., the end of therapy)

Awards & highlights

Study Summary

This trial is testing a therapy to help people with aphasia, who have difficulty finding words, be more successful. The therapy will last 10 weeks with 20 sessions. Each session will last 2 hours. The participants will have fMRI scans before and after therapy to see if there are any changes in the brain.

Who is the study for?

This trial is for English-speaking adults with aphasia, a language disorder after brain injury. They must be medically stable, able to move at least in a wheelchair, have good vision and hearing (with aids if needed), finished high school, had their stroke over 6 months ago, and be right-handed.Check my eligibility

What is being tested?

The study tests a therapy called AbSANT aimed at improving word-finding in people with aphasia. Participants will undergo twenty 2-hour sessions over ten weeks. Brain activity changes due to the therapy are measured using fMRI scans before and after the treatment period.See study design

What are the potential side effects?

There may not be direct side effects from the behavioral therapy itself; however, undergoing fMRI scans involves lying still in a large magnet which can cause discomfort or anxiety for some individuals.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at baseline and at approximately 10 weeks (i.e., the end of therapy)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at baseline and at approximately 10 weeks (i.e., the end of therapy)

This trial's timeline: 3 weeks for screening, Varies for treatment, and at baseline and at approximately 10 weeks (i.e., the end of therapy) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in fMRI activation patters from pre- to post-treatment

Therapy Effect Size: Change in word generation performance from pre- to post-treatment measured using a version of Cohen's d

Trial Design

1Treatment groups

Experimental Treatment

Group I: AphasiaExperimental Treatment1 Intervention

Abstract Semantic Association Network Training (AbSANT) Each session will be 2 hours long and will occur twice each week for a total of 20 sessions.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Abstract Semantic Association Network Training (AbSANT)

2018

N/A

~20

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Penn State UniversityLead Sponsor

355 Previous Clinical Trials

125,738 Total Patients Enrolled

1 Trials studying Aphasia

40 Patients Enrolled for Aphasia

Chaleece W Sandberg, Ph.D.Principal InvestigatorThe Pennsylvania State University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is access to this trial available for participants right now?

"Clinicaltrials.gov supports the notion that this study is presently recruiting patients, with its initial posting on September 25th 2018 and latest revision taking place at December 22nd 2021."

Answered by AI

How many participants are currently engaged in this research endeavor?

"Affirmative. According to the data hosted on clinicaltrials.gov, this medical trial has been open for recruitment since September 25th 2018 and was last updated on December 22nd 2021. The research team is looking for a total of 22 patients at one location."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Analysis of Brain Activity to Uncover Brain-behavior Relationships Related to Therapy Outcomes in Aphasia

Chaleece Sandberg 2018. "Analysis of Brain Activity to Uncover Brain-behavior Relationships Related to Therapy Outcomes in Aphasia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03550092.