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Transcranial Direct Current Stimulation

tDCS plus computerized naming therapy for Stroke

N/A
Waitlist Available
Led By Rajani Sebastian, PhD, CCC-SLP
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up pre-treatment and at 2 months post-treatment
Awards & highlights

Study Summary

This study is evaluating whether a combination of tDCS and computerized naming therapy may help improve language abilities for individuals with post-stroke aphasia.

Eligible Conditions
  • Stroke

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~pre-treatment and at 2 months post-treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and pre-treatment and at 2 months post-treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Accuracy of Naming Untrained Pictures (Philadelphia Naming Test:PNT) Pre-treatment to Post-treatment
Secondary outcome measures
Change in Accuracy of Naming Untrained Pictures (Philadelphia Naming Test:PNT) Pre-treatment to 2 Months Post-treatment.
Change in Accuracy of Naming Untrained Pictures (Philadelphia Naming Test:PNT)Pre-treatment to 2 Weeks Post-treatment.
Change in Discourse Ability Pre- Treatment to 2 Weeks Post-treatment.
+8 more

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: tDCS plus computerized naming therapyActive Control2 Interventions
Anodal or cathodal tDCS, 2 milliamps (mA) plus computerized naming treatment for 15 sessions (20 minutes per each 45 minute treatment session) over the course of 3-5 weeks.The electrical current will be administered to the right cerebellum. The stimulation will be delivered at an intensity of 2 mA for a maximum of 20 minutes. Language therapy will be a computer delivered naming +picture matching task.
Group II: Sham plus computerized naming therapyPlacebo Group2 Interventions
Sham tDCS plus computerized naming treatment for 15 sessions (20 minutes per each 45 minute treatment session) over the course of 3-5 weeks. Current will be administered in the in a ramp like fashion for 15-30 seconds but then the current is gradually decreased and drop to 0 mA. Language therapy will be a computer delivered naming +picture matching task.

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,263 Previous Clinical Trials
14,823,133 Total Patients Enrolled
33 Trials studying Stroke
28,890 Patients Enrolled for Stroke
National Institute on Deafness and Other Communication Disorders (NIDCD)NIH
330 Previous Clinical Trials
178,439 Total Patients Enrolled
25 Trials studying Stroke
1,567 Patients Enrolled for Stroke
Rajani Sebastian, PhD, CCC-SLPPrincipal InvestigatorJohns Hopkins University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Cerebellar Transcranial Direct Current Stimulation and Aphasia Treatment
2016. "Cerebellar Transcranial Direct Current Stimulation and Aphasia Treatment". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02901574.
~4 spots leftby Apr 2025
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