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Transcatheter Aortic Valve Replacement

HLT Transcatheter Aortic Valve System for Aortic Valve Stenosis (RADIANT Trial)

N/A

Waitlist Available

Led By James Hermiller, MD

Research Sponsored by HLT Inc.

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up throughout the 5 year follow up period

Awards & highlights

RADIANT Trial Summary

This trial is testing a new system for aortic valve replacement in people who are at high risk for the surgery. The goal is to see if it is safe and works well.

RADIANT Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ throughout the 5 year follow up period

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~throughout the 5 year follow up period

This trial's timeline: 3 weeks for screening, Varies for treatment, and throughout the 5 year follow up period for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Primary Endpoint: Mortality at 30 days

Secondary outcome measures

Medical Devices

Secondary Performance Endpoint 2: Post-procedural Valve Performance

Secondary Safety Endpoint 3: Adverse Events

RADIANT Trial Design

1Treatment groups

Experimental Treatment

Group I: HLT Transcatheter Aortic Valve SystemExperimental Treatment1 Intervention

Transcatheter aortic valve replacement with HLT Transcatheter Aortic Valve System

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

HLT Transcatheter Aortic Valve System

2014

N/A

~20

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

HLT Inc.Lead Sponsor

5 Previous Clinical Trials

20 Total Patients Enrolled

4 Trials studying Aortic Valve Stenosis

20 Patients Enrolled for Aortic Valve Stenosis

James Hermiller, MDPrincipal InvestigatorSt. Vincent Heart Center of Indian

3 Previous Clinical Trials

13,957 Total Patients Enrolled

Dean Kereiakes, MDPrincipal InvestigatorThe Christ Hospital

4 Previous Clinical Trials

3,247 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants still being enrolled for this research study?

"As per the clinicaltrials.gov registry, this clinical trial is actively seeking subjects for testing. The listing of this medical experiment was first posted on April 27th 2017 and modified most recently on June 29th 2022."

Answered by AI

How many healthcare facilities have initiated this research experiment?

"The Lindner Center for Research and Education at the Christ Hospital in Cincinnati, Ohio, Baylor Scott & White The Heart Hospital Plano in Plano, Texas, and NYU Langone Medical Center are among the multiple clinical trial sites running this medical study. Other 4 participating locations have also been identified."

Answered by AI

How many participants are currently undergoing treatment in this clinical experiment?

"Correct. Clinicaltrials.gov confirms that this clinical study, which was first uploaded on April 27th 2017, is actively looking for participants. Approximately 35 patients across 4 different sites need to be enrolled in the trial."

Answered by AI

Recent research and studies

Circulation: Cardiovascular InterventionsJournal

Transcatheter Aortic Valve Replacement with the HLT Meridian Valve

Rodés-Cabau, Josep, Mathew R. Williams, Harindra C. Wijeysundera, Dean J. Kereiakes, Jean-Michel Paradis, Cezar Staniloae, Muhamed Saric, Sam Radhakrishnan, Robert F. Wilson, and Spencer H. Kubo. 2019. “Transcatheter Aortic Valve Replacement with the HLT Meridian Valve”. Circulation: Cardiovascular Interventions. Ovid Technologies (Wolters Kluwer Health). doi:10.1161/circinterventions.119.008053.

Circulation: Cardiovascular InterventionsJournal

Transcatheter Aortic Valve Replacement with the HLT Meridian Valve

clinicaltrials.govStudy

Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Early Feasibility Trial

2017. "Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Early Feasibility Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02799823.