DINOSAUR Program for Anxiety in Autism

RM
AK
Overseen ByAmy Keefer, PhD
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new program called DINOSAUR (DINO Strategies for Anxiety and Fear of Uncertainty Reduction) to reduce anxiety in preschool children with autism. Researchers aim to determine the program's effectiveness and assess whether families find it easy and practical to use. The trial seeks young children diagnosed with anxiety issues, such as separation anxiety or social anxiety, who can participate in group activities. As an unphased trial, this study offers families the chance to contribute to innovative research that could enhance anxiety management for children with autism.

Will I have to stop taking my current medications?

The trial information does not specify whether participants need to stop taking their current medications.

What prior data suggests that the DINOSAUR intervention is safe for preschool children with autism spectrum disorder?

Research has shown that the DINOSAUR program helps young children with autism manage anxiety by involving both the children and their parents. Previous studies found that this approach, which combines cognitive-behavioral therapy (CBT) with strategies for handling uncertainty, is generally well-received by participants.

In terms of safety, no major negative effects have been reported from using the DINOSAUR program. It focuses on teaching skills and coping strategies, which are non-invasive and safe for young children. The program's safety is further supported by its similarity to other CBT-based methods, which are widely used and considered safe for children with anxiety. Overall, evidence suggests that the DINOSAUR program is a safe option for reducing anxiety in preschool children with autism.12345

Why are researchers excited about this trial?

The DINOSAUR intervention for anxiety in preschool children with autism spectrum disorder (ASD) is unique because it focuses specifically on reducing anxiety and fear of uncertainty, which are common challenges in this group. Unlike typical treatments that might rely on medication or general behavioral therapy, DINOSAUR is a targeted strategy designed to address these specific emotional responses. Researchers are excited about this approach because it could offer a more tailored and potentially more effective way to help young children with ASD manage anxiety, ultimately improving their daily functioning and quality of life.

What evidence suggests that the DINOSAUR program might be an effective treatment for anxiety in preschool children with autism?

Research has shown that the DINOSAUR program, designed to help children with autism manage anxiety, is promising. In earlier studies, this program taught both children and their parents ways to reduce anxiety and handle uncertainty. These studies found that families attended regularly and rarely dropped out, indicating that they found the program helpful and easy to follow. The program uses a mix of techniques to change thinking patterns and address uncertainty, a major component of anxiety. Early results suggest that this approach could effectively lower anxiety symptoms in young autistic children.12367

Are You a Good Fit for This Trial?

Inclusion Criteria

DSM-5 diagnoses of Separation Anxiety, Social Anxiety, and/or Generalized Anxiety Disorder and/or the distinct diagnosis of Other Social Fear based on the results of the Anxiety Disorders Interview Schedule/ASA
Age 4 years 0 months to 6 years 11 months
NVIQ ≥ 85 based on Mullen Scales of Early Learning or Stanford Binet 5
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Waitlist

Participants are placed on a 12-week waitlist before starting the intervention

12 weeks

Treatment

Participants receive the DINOSAUR intervention, a CBT program modified for young children with ASD

12 weeks

Follow-up

Participants are monitored for changes in anxiety and ASD symptoms after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • DINO Strategies for Anxiety and fear of Uncertainty Reduction (DINOSAUR)
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: TreatmentExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Lead Sponsor

Trials
93
Recruited
25,200+

Organization for Autism Research

Collaborator

Trials
7
Recruited
110+

Citations

DINO RCT - Treating Anxiety in Children With AutismThis 14 week intervention teaches parents and children strategies to reduce anxiety and intolerance of uncertainty, an underlying construct of anxiety.
2.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/34635048/
an integrated cognitive-behavioral treatment for anxiety in ...DINOSAUR works with young children and their parents to deliver CBT along with interventions targeting IU and parental accommodation.
DINOSAUR: an integrated cognitive-behavioral treatment for ...The purpose of this article is to describe the development of a novel, integrated anxiety treatment model, DINO Strategies for Anxiety and ...
Anxiety Intervention for Preschool Children With ASDThis study pilots the DINO Strategies for Anxiety and fear of Uncertainty Reduction (DINOSAUR) program, which is an integrated treatment program that utilizes ...
Targeting Anxiety Treatment for Young Autistic ChildrenOverall findings support DINOSAUR's feasibility and acceptability. Attrition was low (14.3%) and group attendance was high (96%), indicating ...
DINOSAUR: an integrated cognitive-behavioral treatment ...Indeed, several research groups are currently testing IU-focused treatments such as DINO Strategies for Anxiety and IU Reduction (DINOSAUR; Keefer & Vasa, 2021) ...
Anxiety Intervention for Preschool Children With ASDThe DINOSAUR treatment is unique because it specifically targets intolerance of uncertainty (IU), which is a key factor in maintaining anxiety. Unlike other ...
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