← Back to Search

Group Receiving Active Stimulation and Sham Stimulation on Separate Days (All Participants) for Anxiety Disorders

Q: Which individuals are eligible to participate in this clinical investigation?

Individuals aged between 18 and 65 years diagnosed with <a href="https://www.withpower.com/clinical-trials/anxiety">anxiety</a> disorders are eligible to participate in the trial. A total of 40 participants are sought for this study.

Q: Is the process of enrolling participants currently underway for this clinical trial?

As documented on clinicaltrials.gov, the current status of this medical trial indicates that recruitment is not ongoing. The trial was initially registered on April 1st, 2024, with the most recent update recorded on February 20th, 2024. Despite this particular study being inactive in its patient search phase currently, there are a total of 430 other trials actively seeking participants presently.

Q: Is there an age criterion that excludes individuals over 35 years old from participating in this clinical study?

The study is seeking individuals over 18 years of age but under 65 years of age to participate in the clinical trial.

N/A

Waitlist Available

Led By Christopher Sege, PhD

Research Sponsored by Medical University of South Carolina

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Meets criteria for an anxiety disorder (Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Specific Phobia), posttraumatic stress disorder, obsessive-compulsive disorder, or current adjustment disorder with anxiety

Age between 18-65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up during session (approx. 45 minutes)

Awards & highlights

Study Summary

This trial is testing a new technology called transcranial focused ultrasound (tFUS) to see if it can help people with anxiety or related concerns manage their emotions better. Participants will come in for

Who is the study for?

This trial is for individuals who have recently started treatment for anxiety or related issues. They should be able to attend three sessions at the Medical University of South Carolina and participate in tasks involving emotional responses, both with and without brain stimulation via tFUS.Check my eligibility

What is being tested?

The study tests transcranial focused ultrasound (tFUS), a non-invasive brain stimulation method, to see if it can influence how people with anxiety respond to emotional situations. Participants will receive either active tFUS that temporarily alters brain activity or sham (inactive) tFUS.See study design

What are the potential side effects?

Since this is a non-invasive procedure, side effects are expected to be minimal but may include temporary discomfort or mild headaches from the ultrasound application or sensors worn during the study.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have been diagnosed with an anxiety disorder or PTSD.

Select...

I am between 18 and 65 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ during session (approx. 45 minutes)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~during session (approx. 45 minutes)

This trial's timeline: 3 weeks for screening, Varies for treatment, and during session (approx. 45 minutes) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Fear-Potentiated Startle Reflex

Secondary outcome measures

Change in Electroencephalography (EEG)-Assessed Contingent Negative Variation During Escape/ Avoidance Preparation

Change in Electroencephalography (EEG)-Assessed N200 During Implicit Approach/ Avoid Bias Assessment

Change in Electroencephalography (EEG)-Assessed Theta-Band Power During Behavioral Tasks

+5 more

Other outcome measures

Task-Related Regional Brain Activation

Trial Design

1Treatment groups

Experimental Treatment

Group I: Group Receiving Active Stimulation and Sham Stimulation on Separate Days (All Participants)Experimental Treatment2 Interventions

All participants will receive active stimulation and non-active (sham) stimulation on different days. Before the stimulation sessions, all participants will complete experimental tasks during functional magnetic resonance imaging. On the next two study days, all participants will complete tasks before and after receiving active transcranial focused ultrasound (tFUS) on one day and sham (non-active) tFUS on another day. Stimulation (active or sham) is conducted briefly (< 10 minutes) in between tasks, not during tasks.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor

933 Previous Clinical Trials

7,394,575 Total Patients Enrolled

14 Trials studying Anxiety Disorders

1,023 Patients Enrolled for Anxiety Disorders

Christopher Sege, PhDPrincipal InvestigatorMedical University of South Carolina

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Which individuals are eligible to participate in this clinical investigation?

"Individuals aged between 18 and 65 years diagnosed with anxiety disorders are eligible to participate in the trial. A total of 40 participants are sought for this study."

Answered by AI

Is the process of enrolling participants currently underway for this clinical trial?

"As documented on clinicaltrials.gov, the current status of this medical trial indicates that recruitment is not ongoing. The trial was initially registered on April 1st, 2024, with the most recent update recorded on February 20th, 2024. Despite this particular study being inactive in its patient search phase currently, there are a total of 430 other trials actively seeking participants presently."

Answered by AI