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Behavioural Intervention

Active tDCS for Anxiety Disorders

N/A
Waitlist Available
Led By Thomas Adams, PhD
Research Sponsored by Thomas Adams
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during extinction recall on day 3 of the experimental protocol.
Awards & highlights

Study Summary

This trial will test whether tDCS can improve fear extinction learning and memory in healthy volunteers.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediately prior to and following administration of tdcs. change in connectivity from pre to post stimulation (delta) will be modeled and used as the dependent variable.
This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately prior to and following administration of tdcs. change in connectivity from pre to post stimulation (delta) will be modeled and used as the dependent variable. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Event related brain activation during extinction learning
Event related brain activation during extinction recall
Fractional amplitude of low frequency fluctuations (fALFF)
+2 more
Secondary outcome measures
Functional connectivity during extinction learning
Functional connectivity during extinction recall
Functional connectivity measure of tDCS

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Active tDCSActive Control1 Intervention
Current will be ramped in/out for 30 seconds at the begging and end of a 20-minute period and a constant current will be delivered for the 20-minutes between ramping.
Group II: Sham tDCSPlacebo Group1 Intervention
Current will be ramped in/out for 30 seconds at the begging and end of a 20-minute period during which no stimulation will be delivered.

Find a Location

Who is running the clinical trial?

Thomas AdamsLead Sponsor
3 Previous Clinical Trials
124 Total Patients Enrolled
National Institute of Mental Health (NIMH)NIH
2,786 Previous Clinical Trials
2,689,632 Total Patients Enrolled
157 Trials studying Anxiety Disorders
65,321 Patients Enrolled for Anxiety Disorders
Thomas Adams, PhD4.39 ReviewsPrincipal Investigator - University of Kentucky
Medical School - University of Kentucky, Doctor of Medicine
Saint Elizabeth's Medical Center (Residency)
1 Previous Clinical Trials
26 Total Patients Enrolled
5Patient Review
Dr. Adams was very engaging, his interest was not only for my current issues but my past as well in order to get to the root of the issue. Dr. Adams was an awesome listener with a great personality.

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this experimental program accept individuals of a certain age and above?

"This trial is open to participants who have attained the age of majority and are below their 55th birthday."

Answered by AI

What is the overall enrollment in this trial?

"Correct. According to information hosted on clinicaltrials.gov, this medical trial is actively recruiting; the initial posting was made back in April of 2019 and it has been updated as recently as June 23rd 2022. 64 patients are needed from one single centre for enrollment."

Answered by AI

May I be a part of this medical experiment?

"To be considered for participation, applicants must suffer from anxiety and fall within the ages of 18 to 55. The total number of participants that will be accepted is 64 individuals."

Answered by AI

Is enrollment for this study still open?

"Confirmed by clinicaltrials.gov, this scientific investigation is presently seeking out participants to take part in the trial. It was initially listed on April 9th 2019 and then last revised June 23rd 2022."

Answered by AI

Who else is applying?

What state do they live in?
Kentucky
What site did they apply to?
University of Kentucky
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
1

Why did patients apply to this trial?

I have taken more than 6 different medications over the course of my lifetime and none have ever brought me to even a stable place. My dna has me as predetermined for ptsd 97%, bipolar/schizophrenic 77%. Have never been diagnosed with anything other than major depressive Would like to try something to help me feel better or at least stable. Thanks for your time.
PatientReceived no prior treatments
Recent research and studies
clinicaltrials.govStudy
Transcranial Direct Current Stimulation and Fear Extinction
Thomas Adams 2019. "Transcranial Direct Current Stimulation and Fear Extinction". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03907917.
~11 spots leftby Apr 2025
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