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Behavioral Intervention

IntelliCare Plus for Depression and Anxiety Disorders

N/A
Recruiting
Led By Jessica M Lipschitz, PhD
Research Sponsored by Brigham and Women's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 18-75
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up for 3 hours after each decision point, over the 8-week intervention period
Awards & highlights

Study Summary

This trial is testing how well two different strategies- automated messages and coach support- improve patient engagement with a mobile app intervention for depression and anxiety.

Who is the study for?
This trial is for Mass General Brigham primary care patients aged 18-75 with significant symptoms of depression or anxiety, who own a smartphone. It's not for those with bipolar I/II, psychotic disorders, unstable medical conditions that could interfere with participation, or current substance use disorder.Check my eligibility
What is being tested?
The study tests how to boost patient involvement in using the IntelliCare Plus app for treating depression and/or anxiety. It compares two methods: automated motivational messages and coach support to see which one increases engagement more effectively.See study design
What are the potential side effects?
Since this trial involves digital interventions rather than medications, traditional side effects are not expected. However, users may experience discomfort or stress from regular app usage or emotional responses to content.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 18 and 75 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~for 3 hours after each decision point, over the 8-week intervention period
This trial's timeline: 3 weeks for screening, Varies for treatment, and for 3 hours after each decision point, over the 8-week intervention period for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Intervention Engagement Within 3 Hours Following a Decision Point - Proximal (Short-Term)
Minutes of Intervention Use - Distal (Long-Term)
Secondary outcome measures
Anxiety Disorders
Change in Patient Health Questionnaire-8 (PHQ-8) Self-Report Scale Score - Distal (Long-Term)

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: IntelliCare with Coach SupportExperimental Treatment1 Intervention
IntelliCare Plus mobile application intervention with one engagement strategy, coach support.
Group II: IntelliCare with Automated Motivational Messaging and Coach SupportExperimental Treatment1 Intervention
IntelliCare Plus mobile application intervention with two engagement strategies, automated motivational messaging and coach support.
Group III: IntelliCare with Automated Motivational MessagingExperimental Treatment1 Intervention
IntelliCare Plus mobile application intervention with one engagement strategy, automated motivational messaging.
Group IV: IntelliCare AloneActive Control1 Intervention
IntelliCare Plus mobile application intervention with no additional engagement strategy applied.

Find a Location

Who is running the clinical trial?

Brigham and Women's HospitalLead Sponsor
1,609 Previous Clinical Trials
11,470,251 Total Patients Enrolled
27 Trials studying Depression
115,697 Patients Enrolled for Depression
National Institute of Mental Health (NIMH)NIH
2,783 Previous Clinical Trials
2,689,073 Total Patients Enrolled
665 Trials studying Depression
251,358 Patients Enrolled for Depression
Jessica M Lipschitz, PhDPrincipal InvestigatorBrigham and Women's Hospital
1 Previous Clinical Trials
12 Total Patients Enrolled
1 Trials studying Depression
12 Patients Enrolled for Depression

Media Library

IntelliCare Plus (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05555875 — N/A
Depression Research Study Groups: IntelliCare with Automated Motivational Messaging and Coach Support, IntelliCare with Automated Motivational Messaging, IntelliCare with Coach Support, IntelliCare Alone
Depression Clinical Trial 2023: IntelliCare Plus Highlights & Side Effects. Trial Name: NCT05555875 — N/A
IntelliCare Plus (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05555875 — N/A
Depression Patient Testimony for trial: Trial Name: NCT05555875 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do I fulfill the requirements to join this experiment?

"To be considered for this depression trial, potential participants must inhabit the age range of 18-75 years old. Currently, 76 individuals are being recruited."

Answered by AI

Is the cut-off age for entry into this clinical trial 45 years or younger?

"To be eligible for this trial, participants must fall within the age range of 18 and 75."

Answered by AI

Are there still openings for participants in this clinical experiment?

"The medical trial advertised on clinicialtrials.gov is no longer looking for candidates, as the advertisement was initially posted on February 1st 2023 and last updated November 14th 2022. Nevertheless, there are still numerous other ongoing trials in search of participants at this time with a total of 1,456 experiments recruiting patients ."

Answered by AI

Who else is applying?

What state do they live in?
New York
California
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?
3+

What questions have other patients asked about this trial?

Is this in person? Or remote?
PatientReceived no prior treatments

Why did patients apply to this trial?

I tried everything I can think of for anxiety and depression. Nothing seems to help. I'll try anything.
PatientReceived no prior treatments
I’m so sick of anxiety all the time and I really don’t want to take benzos but everything else I have tried just hasn’t worked for me.
PatientReceived no prior treatments
Recent research and studies
clinicaltrials.govStudy
Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II
Jessica M. Lipschitz, Ph.D. 2023. "Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05555875.
All > Anxiety Disorder
~40 spots leftby Mar 2025
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