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Computational Cognitive Training for Anhedonia in Depression

N/A
Waitlist Available
Research Sponsored by University of California, San Diego
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change between pre-training and post-training assessments (about 20 min)
Awards & highlights

Study Summary

This trialwill investigate if a special computer-based training can boost reward sensitivity and reduce anhedonia in people with depression and anxiety. It could help develop better treatments for reward processing deficits.

Eligible Conditions
  • Anhedonia
  • Depression

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change between pre-training and post-training assessments (about 20 min)
This trial's timeline: 3 weeks for screening, Varies for treatment, and change between pre-training and post-training assessments (about 20 min) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Neural Tracking of Reward Expectation
Positive Affect
Reward Maximization

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: High Reward - High VarianceExperimental Treatment1 Intervention
Group II: High Reward - Low VarianceActive Control1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
High Reward - High Variance
2022
N/A
~50

Find a Location

Who is running the clinical trial?

University of California, San DiegoLead Sponsor
1,120 Previous Clinical Trials
1,521,585 Total Patients Enrolled
1 Trials studying Anhedonia
129 Patients Enrolled for Anhedonia

Media Library

Computational Cognitive Training Clinical Trial Eligibility Overview. Trial Name: NCT05383248 — N/A
Anhedonia Research Study Groups: High Reward - High Variance, High Reward - Low Variance
Anhedonia Clinical Trial 2023: Computational Cognitive Training Highlights & Side Effects. Trial Name: NCT05383248 — N/A
Computational Cognitive Training 2023 Treatment Timeline for Medical Study. Trial Name: NCT05383248 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do I meet the criteria for enrollment in this trial?

"This clinical trial seeks 50 people between the ages of 18-65 who are suffering from anhedonia. To be considered, applicants must meet certain conditions including: having a Major Depressive Disorder (MDD) or Generalized Anxiety Disorder (GAD), rating below 7 on the Snaith-Hamilton Pleasure Scale (SHAPS) and under 25 in the Positive Affect subscale from the Positive And Negative Affect Scale (PANAS). Additionally, participants will need to have normal vision and hearing as well as fluency in English for proper comprehension of testing procedures."

Answered by AI

Does this trial consider applicants who are over 45 years of age?

"As outlined in the study's inclusion criteria, applicants need to be aged between 18 and 65."

Answered by AI

Does the study have a limit on how many participants it can enroll?

"Affirmative. According to information hosted on clinicaltrials.gov, the recruitment of participants for this medical study is taking place at present - it was first listed in September 14th 2022 and its details were last updated on October 17th 2022. The aim is to have 50 patients enrolling from a single site."

Answered by AI

Is this experiment actively enrolling participants?

"Affirmative. The clinicaltrials.gov data indicate that this medical experiment, which was first listed on September 14th 2022, is actively searching for volunteers. 50 patients have to be enlisted from a single healthcare facility."

Answered by AI
~19 spots leftby Apr 2025