1000 Participants Needed

Registry for Coronary Artery Dissection

(SCAD Trial)

Recruiting at 27 trial locations
EK
EK
Overseen ByEsther Kim, MD, MPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: SCAD Alliance
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to gather information on individuals who have experienced spontaneous coronary artery dissection (SCAD), a condition where a tear forms in a heart blood vessel. By collecting and analyzing participant data, researchers aim to develop better guidelines for preventing SCAD or preventing recurrence. The study will include individuals newly diagnosed with SCAD or with a past diagnosis confirmed by specific heart tests. Participants should not have coronary issues related to other causes, such as atherosclerosis (the build-up of fats in the arteries). As an unphased study, this trial offers participants the opportunity to contribute to groundbreaking research that could lead to improved prevention strategies for SCAD.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Why are researchers excited about this trial?

Researchers are excited about the International Spontaneous Coronary Artery Dissection (SCAD) Registry because it aims to gather vital insights into a condition that is not well understood. Unlike many heart conditions that have established treatment protocols, SCAD often lacks a clear standard of care and can affect otherwise healthy individuals, particularly women. By observing patients over time, the registry seeks to uncover patterns and risk factors that could lead to better diagnosis, management strategies, and possibly preventative measures for SCAD. This approach is unique because it focuses on understanding the condition itself rather than testing a specific drug or intervention, which could significantly enhance future treatment options and improve patient outcomes.

Who Is on the Research Team?

EK

Esther Kim, MD

Principal Investigator

Chair, Steering Committee

MW

Malissa Wood, MD

Principal Investigator

Member, Steering Committee

SN

Sahar Naderi, MD

Principal Investigator

Member, Steering Committee

Are You a Good Fit for This Trial?

Inclusion Criteria

Inpatient wards of the enrolling medical centers during the acute presentation of SCAD, or Outpatient cardiovascular clinics of enrolling medical centers.
Diagnosis of SCAD or history of SCAD based on coronary angiography, either catheter-based or coronary CTA
Suspected SCAD by coronary angiography

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

Data Collection

Prospective and retrospective collection of clinical and psychosocial data related to SCAD

Continuous for an average of 3 years

Follow-up

Participants are monitored for clinical and psychosocial outcomes, including recurrent myocardial infarction and mental health assessments

Continuous for an average of 3 years

What Are the Treatments Tested in This Trial?

Interventions

  • Observational Study

Find a Clinic Near You

Who Is Running the Clinical Trial?

SCAD Alliance

Lead Sponsor

Trials
1
Recruited
1,000+

PERFUSE Study Group

Collaborator

Trials
1
Recruited
1,000+

PERFUSE Academic Research Organization

Collaborator

Trials
1
Recruited
1,000+
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