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CompuFlo thoracic epidural placement for Thoracic Epidural Anesthesia

N/A
Waitlist Available
Led By Yatish S Ranganath, MD
Research Sponsored by YATISH SIDDAPURA RANGANATH
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 20 minutes post administration of epidural test dose
Awards & highlights

Study Summary

This trial is comparing the success rates of two different approaches to thoracic epidural placement - the traditional method and the CompuFlo system.

Eligible Conditions
  • Thoracic Epidural Anesthesia

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 20 minutes post administration of epidural test dose
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 20 minutes post administration of epidural test dose for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of Participants With Successful Thoracic Epidural Catheter Placement
Secondary outcome measures
Amount of Time Required to Complete the Procedure
Mean Arterial Pressure at Baseline and 20 Minutes Post Procedure
Number of Participants Who Reported Loss of Cold Sensation at Various Time Points
+4 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: CompuFlo epidural groupExperimental Treatment1 Intervention
This device (CompuFlo) will aid in correct placement of the epidural by electronically sensing pressure in real time and by providing a numerical value on a read out screen to determine a loss of resistance. There is also an audio signal that signals a loss of resistance.
Group II: Traditional epidural groupActive Control1 Intervention
The traditional approach to placing thoracic epidurals by loss-of-resistance technique using a ground glass syringe will be used in this group.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
CompuFlo thoracic epidural placement
2019
N/A
~120

Find a Location

Who is running the clinical trial?

YATISH SIDDAPURA RANGANATHLead Sponsor
1 Previous Clinical Trials
128 Total Patients Enrolled
Yatish S Ranganath, MDPrincipal InvestigatorUniversity of Iowa

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
JamaJournal
Efficacy of Postoperative Epidural Analgesia
Block, Brian M., Spencer S. Liu, Andrew J. Rowlingson, Anne R. Cowan, John A. Cowan, Jr, and Christopher L. Wu. 2003. “Efficacy of Postoperative Epidural Analgesia”. Jama. American Medical Association (AMA). doi:10.1001/jama.290.18.2455.
Archives of SurgeryJournal
Protective Effects of Epidural Analgesia on Pulmonary Complications After Abdominal and Thoracic Surgery
Pöpping, Daniel M.. 2008. “Protective Effects of Epidural Analgesia on Pulmonary Complications After Abdominal and Thoracic Surgery”. Archives of Surgery. American Medical Association (AMA). doi:10.1001/archsurg.143.10.990.
Regional Anesthesia and Pain MedicineJournal
Reliability of Waveform Analysis as an Adjunct to Loss of Resistance for Thoracic Epidural Blocks
Leurcharusmee, Prangmalee, Vanlapa Arnuntasupakul, Daniel Chora De La Garza, Amorn Vijitpavan, Sonia Ah-Kye, Abhidej Saelao, Worakamol Tiyaprasertkul, Roderick J. Finlayson, and De Q.H. Tran. 2015. “Reliability of Waveform Analysis as an Adjunct to Loss of Resistance for Thoracic Epidural Blocks”. Regional Anesthesia and Pain Medicine. BMJ. doi:10.1097/aap.0000000000000313.
Journal of Clinical AnesthesiaJournal
Pressure Waveform-guided Epidural Catheter Placement in Comparison to the Loss-of-resistance Conventional Method
Gong, Yuhua, Haixia Shi, Jie Wu, Danbaila Labu, Junzhi Sun, Haiyan Zhong, Libiao Li, et al.. 2014. “Pressure Waveform-guided Epidural Catheter Placement in Comparison to the Loss-of-resistance Conventional Method”. Journal of Clinical Anesthesia. Elsevier BV. doi:10.1016/j.jclinane.2014.01.015.
~20 spots leftby Apr 2025
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