This trial is evaluating whether Jarrow Formulas Oral Bovine Lactoferrin Supplement will improve 6 primary outcomes in patients with Iron-deficiency. Measurement will happen over the course of delivery (~8 months).
This trial requires 40 total participants across 2 different treatment groups
This trial involves 2 different treatments. Jarrow Formulas Oral Bovine Lactoferrin Supplement is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
Iron deficiency can be cured by blood iron therapy. This is feasible because an adequate proportion of patients are responsive to correction of iron deficiency.
About 25 million Americans in the United States meet the current guidelines for iron intake. For iron-deficiency, around 20 million Americans under the current guidelines require reassurance. Those meeting the current guidelines should continue with their current intake of iron and should check if they are still anemic.
The majority of patients with IDF have not had gastrointestinal bleeding or iron deficiency. Iron deficiency causes increased morbidity after cardiac and vascular disease. It can also be the cause of anemia of chronic disease or other anaemias.
Iron deficiency is common in children and can cause a range of developmental problems and adult health problems including an increased risk of infant mortality. The World Health Organization/International Program for Appropriate Nutrition in the Developmental Period (IPAN) Guidelines highlight the importance of vitamin C and iron in childhood.
Iron-deficiency is a neglected tropical disease and is prevalent in sub-Saharan Africa with an estimated one billion people with iron-deficiency anaemia, half of whom are children. The condition is associated with poor growth, impaired work capacity, poor health and death. An effective treatment with oral iron in sub-Saharan Africa will have major health benefits. This article discusses iron deficiency anaemia, and treatments of iron deficiency.
Signs of iron deficiency involve a variety of ways; there is a shortage of circulating iron or of sufficient amount of iron-binding proteins in blood. Symptoms of iron deficiency include a noticeable anemia, fatigue, a slow response to infection and a preference for iron-rich foods. The condition is rarely asymptomatic and most commonly symptomatic only in women after menopause.\n\n- "
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The Jarrow bovine lactoferrin supplement is not effective either for IBD or autoimmune diseases. It should not be used over the counter for these purposes.
Bovine lactoferrin, when administered as a part of the oral iron treatment, did not change the treatment status of iron-deficient women in this study compared with placebo.
No study of Jarrow formula and oral LB supplementation reported that the Jarrow formula is used alone in patients with iron-deficiency anemia, so that no direct comparison could be done with other oral supplements in this patient population.
There are a number of possible advantages for the use of jarrow bovine lactoferrin formula supplements. They may be useful for improving the iron absorption in case of iron-deficiency diseases. Since their safety and effectiveness was not established during the studies, further clinical trials are recommended in order to evaluate their effectiveness.
This pilot study demonstrates that daily supplementation with 10 g of bovine lactoferrin plus 15 mg/d of oral ferrous sulfate significantly improves self-reported oral health quality of life but not iron status.
Since 2004, there has been significant research in the field of supplements for therapeutic use and over 3000 products have been launched. In this decade, the demand for therapeutic use has grown at the rate of 16% annually, and so has the development of new products. The introduction of a new product requires testing for the efficacy and the safety, and for a new therapeutic product in a disease area where treatment is still in its prototype stage, its mechanism of action is not totally clear. However, there are some new products that are already in use and show efficacy. Also, the quality of a new therapeutic product for therapeutic use needs to be evaluated in terms of its safety, dosage, and safety profile, before its launch.