Acute Intermittent Hypoxia for Lou Gehrig's Disease

UF Clinical Research Center, Gainesville, FL
Lou Gehrig's Disease+1 More ConditionsAcute Intermittent Hypoxia - Other
Eligibility
21 - 75
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test the effects of a single session of interrupted breathing on respiratory and non-respiratory motor function in patients with ALS and healthy controls.

Eligible Conditions
  • Lou Gehrig's Disease
  • Neuromuscular Disease

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
N/A

Study Objectives

2 Primary · 3 Secondary · Reporting Duration: 3 Hours

3 Hours
Maximal Respiratory Pressures
Maximal Voluntary Grip Force
Minute Ventilation
Surface electromyography (EMG)
Ventilatory Drive

Trial Safety

Phase-Based Safety

1 of 3

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

2 Treatment Groups

ALS Group
1 of 2
Healthy Control Group
1 of 2

Experimental Treatment

56 Total Participants · 2 Treatment Groups

Primary Treatment: Acute Intermittent Hypoxia · No Placebo Group · N/A

ALS GroupExperimental Group · 2 Interventions: Sham Acute Intermittent Hypoxia, Acute Intermittent Hypoxia · Intervention Types: Other, Other
Healthy Control GroupExperimental Group · 2 Interventions: Sham Acute Intermittent Hypoxia, Acute Intermittent Hypoxia · Intervention Types: Other, Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3 hours

Who is running the clinical trial?

University of FloridaLead Sponsor
1,274 Previous Clinical Trials
700,031 Total Patients Enrolled
Barbara K Smith, PT, PhDPrincipal InvestigatorUniversity of Florida
3 Previous Clinical Trials
51 Total Patients Enrolled

Eligibility Criteria

Age 21 - 75 · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have been diagnosed with ALS by a doctor.
You are a physically healthy adult.

Frequently Asked Questions

Are persons of age 20 and older being enrolled in this experiment?

"The accepted age ranges for this trial are between 21 and 75, as indicated by the inclusion criteria." - Anonymous Online Contributor

Unverified Answer

Am I eligible to participate in this clinical investigation?

"Applicants to this medical trial must have Oppenheim disease and be between 21 and 75 years old. Approximately 56 patients are needed for the study." - Anonymous Online Contributor

Unverified Answer

How many participants is the trial recruiting?

"Affirmative. Clinicaltrials.gov has records of this clinical trial, which was opened on October 1st 2018, currently seeking participants. In total, 56 individuals are required from 2 different medical sites." - Anonymous Online Contributor

Unverified Answer

Are there available places for participants in this research project?

"According to the clinicaltrials.gov website, this clinical trial is actively recruiting members for participation. Initially posted on October 1st 2018 and last updated July 25th 2022." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.