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Perceptual learning for Lazy Eye

N/A
Waitlist Available
Led By Roger W Li, OD, PhD
Research Sponsored by University of California, Berkeley
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 9 months
Awards & highlights

Study Summary

This trial studies how well different types of treatment work in adults and children with amblyopia.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~9 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 9 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Amblyopic vision
Secondary outcome measures
Spatial vision
Temporal vision

Trial Design

3Treatment groups
Experimental Treatment
Group I: Video gameExperimental Treatment1 Intervention
Patients will be asked to play videogames for a period of time (each therapy session:1-2 hrs, 4-5 sessions/wk for ~1-6 months).
Group II: Perceptual learningExperimental Treatment1 Intervention
Patients will be asked to practice a range of visual discrimination tasks for a period of time (each therapy session:1-2 hrs, 4-5 sessions/wk for ~1-6 months).
Group III: Occlusion therapyExperimental Treatment1 Intervention
The fellow sound will be covered with a standard eye patch for a period of time (1-2 hrs/day, 4-5 days/wk for ~1-3 months). The idea is to push the brain to use the weaker amblyopic eye.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Perceptual learning
2004
N/A
~70
Occlusion therapy
2015
N/A
~50
Video Games
2008
N/A
~210

Find a Location

Who is running the clinical trial?

University of California, BerkeleyLead Sponsor
179 Previous Clinical Trials
721,104 Total Patients Enrolled
National Eye Institute (NEI)NIH
546 Previous Clinical Trials
1,401,944 Total Patients Enrolled
Roger W Li, OD, PhDPrincipal InvestigatorSchool of Optometry, Univeristy of california-Berkeley
2 Previous Clinical Trials
200 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Vision ResearchJournal
Identification of Contrast-defined Letters Benefits from Perceptual Learning in Adults with Amblyopia
Chung, Susana T.L., Roger W. Li, and Dennis M. Levi. 2006. “Identification of Contrast-defined Letters Benefits from Perceptual Learning in Adults with Amblyopia”. Vision Research. Elsevier BV. doi:10.1016/j.visres.2006.06.014.
Frontiers in NeuroscienceJournal
Donepezil Does Not Enhance Perceptual Learning in Adults with Amblyopia: A Pilot Study
Chung, Susana T. L., Roger W. Li, Michael A. Silver, and Dennis M. Levi. 2017. “Donepezil Does Not Enhance Perceptual Learning in Adults with Amblyopia: A Pilot Study”. Frontiers in Neuroscience. Frontiers Media SA. doi:10.3389/fnins.2017.00448.
Journal of NeuroscienceJournal
Prolonged Perceptual Learning of Positional Acuity in Adult Amblyopia: Perceptual Template Retuning Dynamics
Li, R. W, S. A Klein, and D. M Levi. 2008. “Prolonged Perceptual Learning of Positional Acuity in Adult Amblyopia: Perceptual Template Retuning Dynamics”. Journal of Neuroscience. Society for Neuroscience. doi:10.1523/jneurosci.4271-08.2008.
Scientific ReportsJournal
Relieving the Attentional Blink in the Amblyopic Brain with Video Games
Li, Roger W., Charlie V. Ngo, and Dennis M. Levi. 2015. “Relieving the Attentional Blink in the Amblyopic Brain with Video Games”. Scientific Reports. Springer Science and Business Media LLC. doi:10.1038/srep08483.
~5 spots leftby Apr 2025
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