← Back to Search

Light Therapy for Mild Cognitive Impairment

N/A
Recruiting
Led By Mariana Figueiro, PhD
Research Sponsored by Icahn School of Medicine at Mount Sinai
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up one sample will be collected every 30 minutes during each 90 minute study session up to 5 weeks
Awards & highlights

Study Summary

This trial will study the effects of light on memory in people with mild cognitive impairment and compare them to healthy age-matched controls.

Who is the study for?
This trial is for people with mild cognitive impairment or those who are healthy but match the age of participants. They must have specific levels of pigment density in their eyes. It's not open to individuals taking sleep or antidepressant meds, those with certain eye diseases, extensive brain vascular disease, Parkinson's, bipolar disorder, seasonal depression, diabetes, high blood pressure or using beta blockers/melatonin supplements.Check my eligibility
What is being tested?
The study is testing how blue and green light interventions affect melatonin levels and memory by changing the light distribution pattern from 'on-axis' (directed to the center of vision) to 'off-axis' (directed towards the periphery). It involves comparing these effects between people with mild cognitive impairment and healthy controls.See study design
What are the potential side effects?
Potential side effects may include discomfort due to exposure to different lighting conditions which could potentially affect sleep patterns or mood given that light has an influence on circadian rhythms.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one sample will be collected every 30 minutes during each 90 minute study session up to 5 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and one sample will be collected every 30 minutes during each 90 minute study session up to 5 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in melatonin levels

Trial Design

2Treatment groups
Experimental Treatment
Group I: Lighting Intervention GreenExperimental Treatment1 Intervention
Green light (λmax = 522 nm) on and off axis
Group II: Lighting Intervention BlueExperimental Treatment1 Intervention
Blue light (λmax = 451 nm) on and off axis

Find a Location

Who is running the clinical trial?

Icahn School of Medicine at Mount SinaiLead Sponsor
860 Previous Clinical Trials
524,428 Total Patients Enrolled
Mariana Figueiro, PhDPrincipal InvestigatorIcahn School of Medicine
9 Previous Clinical Trials
746 Total Patients Enrolled

Media Library

Lighting Intervention Blue light Clinical Trial Eligibility Overview. Trial Name: NCT05411822 — N/A
Mild Cognitive Impairment Research Study Groups: Lighting Intervention Blue, Lighting Intervention Green
Mild Cognitive Impairment Clinical Trial 2023: Lighting Intervention Blue light Highlights & Side Effects. Trial Name: NCT05411822 — N/A
Lighting Intervention Blue light 2023 Treatment Timeline for Medical Study. Trial Name: NCT05411822 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new volunteers being taken in for this experiment right now?

"That is correct. The listing on clinicaltrials.gov verifies that the trial is currently ongoing and that they are looking for 48 individuals from 1 site."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Understanding Circadian Responses to Light in Persons With Mild Cognitive Impairment
Mariana Figueiro 2021. "Understanding Circadian Responses to Light in Persons With Mild Cognitive Impairment". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05411822.
All > Mild Cognitive Impairment
~12 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top